Evidence map›Paper›PMID 34603663›Full record

ArticleChemical science2021

Zirconium-catalyzed asymmetric Kabachnik-Fields reactions of aromatic and aliphatic aldehydes.

Yijing Dai, Li Zheng, Debarshi Chakraborty, Babak Borhan, William D Wulff

Abstract read
In one paragraph

Article in Chemical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yijing DaiDepartment of Chemistry, Michigan State University East Lansing MI 48824 USA wulff@chemistry.msu.edu.
Li ZhengDepartment of Chemistry, Michigan State University East Lansing MI 48824 USA wulff@chemistry.msu.edu.
Debarshi ChakrabortyDepartment of Chemistry, Michigan State University East Lansing MI 48824 USA wulff@chemistry.msu.edu.
Babak BorhanDepartment of Chemistry, Michigan State University East Lansing MI 48824 USA wulff@chemistry.msu.edu.ORCID https://orcid.org/0000-0002-3193-0732
William D WulffDepartment of Chemistry, Michigan State University East Lansing MI 48824 USA wulff@chemistry.msu.edu.ORCID https://orcid.org/0000-0002-5668-4312

Funding

New Chiral Br??nsted Acids for Asymmetric SynthesisR01GM094478 · NIGMS · MICHIGAN STATE UNIVERSITY · PI WULFF, WILLIAM DEAN · 2011 to 2014
$1.0M
NIGMS NIH HHS R01 GM094478
6 · The paper itself

Abstract

An effective catalyst has been developed for the three-component reaction of aldehydes, anilines and phosphites in an asymmetric catalytic Kabachnik-Fields reaction to give α-aminophosphonates. A catalyst was sought that would give high asymmetric inductions for aromatic and, and more particularly, for aliphatic aldehydes since there has not previously been an effective catalyst developed for this class of aldehydes. The optimal catalyst is prepared from three equivalents of the 7,7'-di-

Identifiers

PMID34603663
PMCPMC8480333

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.