ArticleJournal of clinical and experimental dentistry2021
Enamel remineralization and surface roughness after treatment with herbal-containing toothpastes.
Article in Journal of clinical and experimental dentistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Pomegranate extract in polyphosphate-fluoride mouthwash reduces enamel demineralization.Clinical oral investigations · 2024Trial
- Remineralization of Artificial Caries-like Lesions in Permanent Enamel by MI Paste One: Comparative Physicochemical Outcomes and In Vitro Resistance to Secondary Demineralization.Journal of functional biomaterials · 2026Article
- Navigating fluoride hesitancy: mapping the evidence base for fluoride-free toothpaste alternatives.European journal of pediatrics · 2026Review
- Effect of vegan toothpastes on surface characteristics of human enamel after erosion-abrasion.Brazilian dental journal · 2025Article
- Natural Strategies for Dental Hard-Tissue Remineralization: A Scoping Review of Galla Chinensis and Its Dual Anticaries Action.Clinical, cosmetic and investigational dentistry · 2025Review
- Bioactive silicon-based dental gel associated with a calcium booster for dentin hypersensitivity treatment: A randomized clinical study.Journal of clinical and experimental dentistry · 2024Article
- Evaluating color stability and enamel surface roughness following resin infiltration treatment.Clinical and experimental dental research · 2024Article
- Effectiveness of fluoride-containing toothpastes associated with different technologies to remineralize enamel after pH cycling: an in vitro study.BMC oral health · 2022Article
- Effectiveness of Experimental Whitening Toothpastes Containing Colorants on the Optical Properties of Enamel.TheScientificWorldJournal · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOral care products containing bioactive agents obtained from extracts of plant drugs were launched. This MATERIAL AND
methodsSixty bovine enamel blocks were obtained and divided into 3 thirds: intact (untreated), demineralized (artificial caries lesion), and treated (caries lesion, pH cycling, and brushing with toothpastes). Toothpastes containing herbal compounds contained no fluoride [Galla chinensis (GCH)], low-F concentration [D'Or (DOR); Herbal Bliss (HBL)], or a different fluoride type [Elmex Anticaries (EAC)]. The results were compared to NaF-containing toothpastes: 1450 and 5000 ppm. Enamel blocks were brushed with the toothpastes using a pH-cycling model (7 days). The Knoop hardness (25g/10s) of the surface and the longitudinal sections were then evaluated. The percentage of surface hardness recovery (%SHR) was calculated. The enamel surface roughness, pH, particle size, zeta potential, and polydispersity index of toothpaste slurries were also evaluated. Data were statistically analyzed (α=5%).
resultsNo significance was observed when %SHR was compared (
conclusionsAll toothpastes were able to remineralize the enamel, especially the subsurface, with results equal or better than that of standard toothpastes.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.