Evidence map›Paper›PMID 34603586›Full record

ArticleThe Pan African medical journal2021

Vaccine coverage, timeliness and delay estimated from regional and national cross-sectional surveys in Ethiopia, 2016.

Abram Luther Wagner, Yemesrach Abeje Tefera, Brenda Wilson Gillespie, Bradley Frederick Carlson, Matthew Lester Boulton

Abstract readComparative Study
In one paragraph

Article in The Pan African medical journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Abram Luther WagnerDepartment of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA.
Yemesrach Abeje TeferaDepartment of Public Health, St. Paul´s Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Brenda Wilson GillespieDepartment of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA.
Bradley Frederick CarlsonDepartment of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA.
Matthew Lester BoultonDepartment of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionmeasures of vaccine timing require data on vaccination dates, which may be unavailable. This study compares estimates of vaccine coverage and timing; and compares regression techniques that model these measures in the presence of incomplete data.

methodsthis cross-sectional study used the 2016 Ethiopian Demographic and Health Survey (DHS), and a 2016 survey from Worabe, Ethiopia. Three measures of vaccine uptake were calculated: coverage (regardless of timing), timeliness (within 1 week of recommended administration), and delay (the number of days between the recommended and actual date of vaccination). Vaccine coverage and timeliness were modeled with logistic regressions. After excluding those without dates, vaccine delay was estimated using linear regression or survival analysis. Vaccine delay was also estimated using accelerated failure time (AFT) models.

resultsthe DHS survey included 3819 children aged 12-60 months and the Worabe survey included 484 children aged 12-23 months. In the Worabe survey, vaccine coverage for pentavalent vaccine dose 3 was 87.4%, with 8.6% receiving it within 1 week, and 71.7% within 4 weeks; the median delay was 19 days. Predictors of outcomes were similar in both the Worabe survey and Ethiopian DHS, with the largest numbers of significant associations seen in models with vaccine coverage or delays (with AFT models) as the outcomes.

conclusionestimates of coverage may miss a substantial proportion of infants who have delayed vaccination. Accelerated failure time (AFT) models are useful to estimate vaccine delay because they include information from all respondents (those with full and partial data on vaccination dates) and are agnostic about an age limit for timely vaccination.

Indexed as

Immunization ScheduleChild, PreschoolCross-Sectional StudiesEthiopiaFemaleHealth SurveysHumansImmunization ProgramsInfantMaleModels, StatisticalRegression AnalysisTime FactorsVaccinationVaccination CoverageVaccinesVaccinesEthiopiavaccination timelinessvaccine coveragevaccine delay

Identifiers

PMID34603586
PMCPMC8464200

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.