ArticleCognitive neurodynamics2021
Hard to initiate sleep: a new paradigm for resting-state fMRI.
Article in Cognitive neurodynamics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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Who cites it
4 citing papers in PubMed, 11 citations in OpenAlex.
- Trial
- Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) for Insomnia Disorder: A Narrative Review of Effectiveness, Mechanisms and Recommendations for Clinical Practice.Nature and science of sleep · 2025Review
- Abnormal alterations of regional spontaneous neuronal activity and functional connectivity in insomnia patients with difficulty falling asleep: a resting-state fMRI study.BMC neurology · 2023Article
- EEG-FCV: An EEG-Based Functional Connectivity Visualization Framework for Cognitive State Evaluation.Frontiers in psychiatry · 2022Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A better understanding of the neural mechanism of sleep initiation is helpful for sleep health. Our current study aimed to develop a new paradigm that is suitable for using resting-state functional magnetic resonance imaging (rs-fMRI) to investigate the inability to initiate sleep. We recruited 28 subjects from nearby communities, in addition to traditionally resting-state eyes-closed condition (EC), they were further asked to try-to-sleep (TTS) in the MRI scanner. Independent component analysis (ICA) was used to extract the large-scale brain networks. No significant difference was found between EC and TTS in the amplitude of brain activity, nor the functional connectivity. However, under the condition of TTS, there was a significant negative correlation between functional connectivity and sleep quality. The results suggesting that the stronger the functional connectivity between the visual network and default mode network, the worse the sleep quality. The results of our research presented here suggested the increased integration among the visual thought-related networks of poor sleepers during sleep onset. More importantly, this study attempt to combine the sleep latency test with resting-state fMRI, and it may help us to investigate the neural mechanism of sleep initiation problem. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s11571-020-09659-6.
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Registered trials
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