ReviewEuropean cardiology2021
Timing of Intervention in Asymptomatic Patients with Aortic Stenosis.
Review in European cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Brazilian Guideline for Exercise Test in the Adult Population - 2024.Arquivos brasileiros de cardiologia · 2024Guideline
- Hemodynamic effects of hemodialysis: the interaction between the heart and the arteries.Journal of nephrology · 2025Review
- One-year mortality in patients undergoing aortic valve replacement and its relationship with the extent of myocardial damage scale.Archivos de cardiologia de Mexico · 2025Observational
- Cardiac Rehabilitation in TAVI Patients: Safety and Benefits: A Narrative Review.Medicina (Kaunas, Lithuania) · 2025Review
- Aortic Valve Replacement in the Current Era.Journal of clinical medicine · 2025Review
- Article
- Optimal treatment of asymptomatic patients with severe aortic stenosis: protocol of a prospective, multicentre, registry study.BMJ open · 2023Article
- Asymptomatic Severe and Moderate Aortic Stenosis: Time for Appraisal of Treatment Indications.Structural heart : the journal of the Heart Team · 2023Review
- Prevalence and clinical associations of mitral and aortic regurgitation in patients with aortic stenosis.Echocardiography (Mount Kisco, N.Y.) · 2023Article
- Asymptomatic Severe Aortic Stenosis: Contemporary Evaluation and Management.Heart views : the official journal of the Gulf Heart AssociationReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aortic stenosis is a very common disease. Current guidelines recommend intervention mainly in symptomatic patients; aortic valve replacement can be considered in asymptomatic patients under specific conditions, but the evidence supporting these indications is poor. Continuous advances in both surgical and percutaneous techniques have substantially decreased rates of perioperative complications and mortality; with this in mind, many authors suggest that earlier intervention in patients with severe aortic stenosis, when they are still asymptomatic, may be indicated. This paper summarises what is known about the natural history of severe aortic stenosis and the scientific evidence available about the optimal timing for aortic valve replacement.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.