ArticleComputational intelligence and neuroscience2021
The Role of Medication Data to Enhance the Prediction of Alzheimer's Progression Using Machine Learning.
Article in Computational intelligence and neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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5 citing papers in PubMed, 15 citations in OpenAlex.
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- Review
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Authors and funding
6 authors at 6 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Early detection of Alzheimer's disease (AD) progression is crucial for proper disease management. Most studies concentrate on neuroimaging data analysis of baseline visits only. They ignore the fact that AD is a chronic disease and patient's data are naturally longitudinal. In addition, there are no studies that examine the effect of dementia medicines on the behavior of the disease. In this paper, we propose a machine learning-based architecture for early progression detection of AD based on multimodal data of AD drugs and cognitive scores data. We compare the performance of five popular machine learning techniques including support vector machine, random forest, logistic regression, decision tree, and K-nearest neighbor to predict AD progression after 2.5 years. Extensive experiments are performed using an ADNI dataset of 1036 subjects. The cross-validation performance of most algorithms has been improved by fusing the drugs and cognitive scores data. The results indicate the important role of patient's taken drugs on the progression of AD disease.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.