Evidence map›Paper›PMID 34603299›Full record

ArticleFrontiers in immunology2021

Extracellular Matrix-Induced GM-CSF and Hypoxia Promote Immune Control of

Ainhoa Arbués, Sarah Schmidiger, Michael Kammüller, Damien Portevin

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Experimental dissection of tuberculosis protective immunity: a human perspective.Frontiers in cellular and infection microbiology · 2025
    Review
  8. Article
  9. Transcriptome Architecture of Osteoblastic Cells Infected WithFrontiers in cellular and infection microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ainhoa ArbuésDepartment of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland.
Sarah SchmidigerDepartment of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland.
Michael KammüllerTranslational Medicine-Preclinical Safety, Novartis Institutes for Biomedical Research, Basel, Switzerland.
Damien PortevinDepartment of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland.
University of Basel · CHNovartis (Switzerland) · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several

Indexed as

Mycobacterium tuberculosisCell AggregationCell HypoxiaCells, CulturedExtracellular MatrixGranulocyte-Macrophage Colony-Stimulating FactorGranulomaHumansLeukocytes, MononuclearMacrophagesPhagocytosisReactive Oxygen SpeciesGranulocyte-Macrophage Colony-Stimulating FactorReactive Oxygen Speciesextracellular matrixGM-CSF (granulocyte-macrophage colony-stimulating factor)granulomahypoxiain vitro modeltuberculosis

Identifiers

PMID34603299
PMCPMC8486295
OpenAlexW3200511405

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.