Evidence map›Paper›PMID 34603295›Full record

ArticleFrontiers in immunology2021

Trained Immunity Confers Prolonged Protection From Listeriosis.

Charlotte Théroude, Marta Reverte, Tytti Heinonen, Eleonora Ciarlo, Irene T Schrijver, Nikolaos Antonakos, Nicolas Maillard, Florian Pralong, Didier Le Roy, Thierry Roger

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
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  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. The role of trained immunity in sepsis.Frontiers in immunology · 2024
    Review
  14. CD115Cell reports · 2023
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Oral administration of heat-inactivatedFrontiers in immunology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Charlotte ThéroudeInfectious Diseases Service, Department of Medicine, Lausanne University Hospital and University of Lausanne, Epalinges, Switzerland.
Marta ReverteInfectious Diseases Service, Department of Medicine, Lausanne University Hospital and University of Lausanne, Epalinges, Switzerland.
Tytti HeinonenInfectious Diseases Service, Department of Medicine, Lausanne University Hospital and University of Lausanne, Epalinges, Switzerland.
Eleonora CiarloInfectious Diseases Service, Department of Medicine, Lausanne University Hospital and University of Lausanne, Epalinges, Switzerland.
Irene T SchrijverInfectious Diseases Service, Department of Medicine, Lausanne University Hospital and University of Lausanne, Epalinges, Switzerland.
Nikolaos AntonakosInfectious Diseases Service, Department of Medicine, Lausanne University Hospital and University of Lausanne, Epalinges, Switzerland.
Nicolas MaillardInfectious Diseases Service, Department of Medicine, Lausanne University Hospital and University of Lausanne, Epalinges, Switzerland.
Florian PralongInfectious Diseases Service, Department of Medicine, Lausanne University Hospital and University of Lausanne, Epalinges, Switzerland.
Didier Le RoyInfectious Diseases Service, Department of Medicine, Lausanne University Hospital and University of Lausanne, Epalinges, Switzerland.
Thierry RogerInfectious Diseases Service, Department of Medicine, Lausanne University Hospital and University of Lausanne, Epalinges, Switzerland.
University of Lausanne · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Trained immunity refers to the ability of the innate immune system exposed to a first challenge to provide an enhanced response to a secondary homologous or heterologous challenge. We reported that training induced with β-glucan one week before infection confers protection against a broad-spectrum of lethal bacterial infections. Whether this protection persists over time is unknown. To tackle this question, we analyzed the immune status and the response to

Indexed as

Immunity, InnateAnimalsBone MarrowCytokinesFemaleInflammationListeria monocytogenesListeriosisMiceMice, Inbred C57BLMonocytesNeutrophilsCytokinesimmunometabolisminfectioninnate immunitylisteriamyelopoiesisneutrophilssepsistrained immunity

Identifiers

PMID34603295
PMCPMC8484647
OpenAlexW3199563338

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.