ArticleFrontiers in microbiology2021
Multivariate Analysis in Microbiome Description: Correlation of Human Gut Protein Degraders, Metabolites, and Predicted Metabolic Functions.
Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 27 citations in OpenAlex.
- Advancing fecal volatilome profiling by comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry and image pattern recognition.Analytical and bioanalytical chemistry · 2026Article
- Gut microbiome modulation by cricket, pea, and whey protein using the SHIME in vitro simulator.NPJ science of food · 2026Article
- A genomic atlas of gut clostridia: phylogeny, butyrate, and propionate production.Frontiers in microbiology · 2026Article
- The influence of environment on bacterial co-abundance in the gut microbiomes of healthy human individuals.Communications biology · 2025Article
- May Sulfites in Wine Affect Gut Microbiota? An In Vitro Study of Their Digestion and Interplay with Wine Polyphenols.Journal of agricultural and food chemistry · 2025Article
- The impact of a high-protein diet with strength training on the gastrointestinal microbiota in community-dwelling older adults: subanalysis of a randomized controlled trial.Frontiers in nutrition · 2025Article
- Genetic hypogonadal (Gnrh1bioRxiv : the preprint server for biology · 2024Article
- Characteristics of stachyose-induced effects on gut microbiota and microbial metabolitesFrontiers in nutrition · 2024Article
- Genomic and functional analysis of the mucinolytic speciesFrontiers in microbiology · 2024Article
- Article
- Fecal Microbiota and Associated Volatile Organic Compounds Distinguishing No-Adenoma from High-Risk Colon Adenoma Adults.Metabolites · 2023Article
- Profiling of the intestinal community ofMicrobiome research reports · 2023Article
- β-Glucuronidase Pattern Predicted From Gut Metagenomes Indicates Potentially Diversified Pharmacomicrobiomics.Frontiers in microbiology · 2022Article
- Integrative analysis of gut microbiota and fecal metabolites in metabolic associated fatty liver disease patients.Frontiers in microbiology · 2022Article
- Indole and p-cresol in feces of healthy subjects: Concentration, kinetics, and correlation with microbiome.Frontiers in molecular medicine · 2022Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Protein catabolism by intestinal bacteria is infamous for releasing many harmful compounds, negatively affecting the health status, both locally and systemically. In a previous study, we enriched in protein degraders the fecal microbiota of five subjects, utilizing a medium containing protein and peptides as sole fermentable substrates and we monitored their evolution by 16S rRNA gene profiling. In the present study, we fused the microbiome data and the data obtained by the analysis of the volatile organic compounds (VOCs) in the headspace of the cultures. Then, we utilized ANOVA simultaneous component analysis (ASCA) to establish a relationship between metabolites and bacteria. In particular, ASCA allowed to separately assess the effect of subject, time, inoculum concentration, and their binary interactions on both microbiome and volatilome data. All the ASCA submodels pointed out a consistent association between indole and
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