Evidence map›Paper›PMID 34603226›Full record

ArticleFrontiers in microbiology2021

Evaluation of Droplet Digital PCR Assay for the Diagnosis of Candidemia in Blood Samples.

Biao Chen, Yingguang Xie, Ning Zhang, Wenqiang Li, Chen Liu, Dongmei Li, Shaodong Bian, Yufeng Jiang, Zhiya Yang, Renzhe Li and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Nucleic Acid Amplification Tests forPathogens (Basel, Switzerland) · 2026
    Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Unresolved issues in the diagnosis of catheter related candidemia: A position paper.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2024
    Review
  11. Review
  12. Article
  13. Review
  14. Absolute quantification of viableFrontiers in microbiology · 2023
    Article
  15. Article
  16. Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Biao ChenThe Laboratory of Medical Mycology, Jining No. 1 People's Hospital, Jining, China.
Yingguang XieIntensive Care Unit, Jining No. 1 People's Hospital, Jining, China.
Ning ZhangThe Laboratory of Medical Mycology, Jining No. 1 People's Hospital, Jining, China.
Wenqiang LiIntensive Care Unit, Jining No. 1 People's Hospital, Jining, China.
Chen LiuThe Laboratory of Medical Mycology, Jining No. 1 People's Hospital, Jining, China.
Dongmei LiDepartment of Microbiology and Immunology, Georgetown University Medical Center, Washington, DC, United States.
Shaodong BianThe Laboratory of Medical Mycology, Jining No. 1 People's Hospital, Jining, China.
Yufeng JiangPostdoctoral Mobile Station of Shandong University of Traditional Chinese Medicine, Jinan, China.
Zhiya YangThe Laboratory of Medical Mycology, Jining No. 1 People's Hospital, Jining, China.
Renzhe LiClinical Laboratory, Jining No. 1 People's Hospital, Jining, China.
Yahui FengClinical Medicine College, Jining Medical College, Jining, China.
Xiaojie ZhangPostdoctoral Mobile Station of Shandong University of Traditional Chinese Medicine, Jinan, China.
Dongmei ShiThe Laboratory of Medical Mycology, Jining No. 1 People's Hospital, Jining, China.
Shandong University of Traditional Chinese Medicine · CNGeorgetown University · USJining First People's Hospital · CNJining Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Numerous studies have shown that droplet digital PCR (ddPCR) is a promising tool for the diagnosis of pathogens, especially in samples with low concentrations of pathogenic DNA. An early diagnosis of candidemia is critical for the effective treatment of patients. In this study, we evaluated the sensitivity and specificity of ddPCR assay for

Indexed as

blood samplescandidemiadiagnosisdroplet digital PCRsensitivityspecificity

Identifiers

PMID34603226
PMCPMC8480469
OpenAlexW3196997218

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.