Evidence map›Paper›PMID 34603071›Full record

ArticleFrontiers in physiology2021

Mechanism of Ulcerative Colitis-Aggravated Liver Fibrosis: The Activation of Hepatic Stellate Cells and TLR4 Signaling Through Gut-Liver Axis.

Yu-Feng Liu, Guo-Chao Niu, Chen-Yang Li, Jin-Bo Guo, Jia Song, Hui Li, Xiao-Lan Zhang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. International journal of molecular sciences · 2025
    Article
  3. [CompoundNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2025
    Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yu-Feng LiuDepartment of Gastroenterology, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
Guo-Chao NiuDepartment of Gastroenterology, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
Chen-Yang LiDepartment of Gastroenterology, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
Jin-Bo GuoDepartment of Gastroenterology, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
Jia SongDepartment of Gastroenterology, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
Hui LiDepartment of Gastroenterology, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
Xiao-Lan ZhangDepartment of Gastroenterology, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
Hebei Medical University · CNSecond Hospital of Hebei Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

gut-liver axishepatic stellate cellsintestinal homeostasisintestinal tight junctionliver fibrosisTLR4 signalingulcerative colitis

Identifiers

PMID34603071
PMCPMC8484790
OpenAlexW3199029722

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.