ArticleFrontiers in aging neuroscience2021
Characterization of Age-Related Differences in the Human Choroid Plexus Volume, Microstructural Integrity, and Blood Perfusion Using Multiparameter Magnetic Resonance Imaging.
Article in Frontiers in aging neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
70 citing papers in PubMed, 2 syntheses or guidelines pooled it, 110 citations in OpenAlex.
- Choroid plexus volume in brain disorders: a systematic review.Fluids and barriers of the CNS · 2025Pooled it
- Choroid plexus volume in multiple sclerosis: a systematic review and meta-analysis of an emerging imaging biomarker.European journal of medical research · 2025Pooled it
- The impaired hemodynamics of choroid plexus and its interactions within the glymphatic system in Parkinson's disease.GeroScience · 2026Article
- Regional choroid plexus calcifications and their associations with aging, brain structure, and disease.bioRxiv : the preprint server for biology · 2026Article
- Choroid Plexus Microstructural Alterations Link Glymphatic Dysfunction and White Matter Degeneration in Parkinson's Disease.CNS neuroscience & therapeutics · 2026Article
- Simultaneous measurement of water transport across the blood-brain and blood-CSF barrier in the human brain with arterial spin labeling MRI.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026Article
- The choroid plexus, cognitive decline, and incident dementia: insights from the UK Biobank.Molecular psychiatry · 2026Article
- Lifespan Modeling of Choroid Plexus Volume in Multiple Sclerosis and Its Dynamic Associations With Clinical, MRI, and HLA Susceptibility.Neurology(R) neuroimmunology & neuroinflammation · 2026Article
- Post-gadolinium T1 alterations in Parkinson's disease and essential tremor.NPJ Parkinson's disease · 2026Article
- Diurnal choroid plexus function in mice depends on sex, age, and amyloid-β status.Communications biology · 2026Article
- The influence of vascular risk factors and aging on choroid plexus enlargement.European radiology · 2026Article
- Morphological and Molecular Characteristics of Choroid Plexus Epithelium in Aged Brains.International journal of molecular sciences · 2026Review
- Choroid plexus enlargement associates with serum neurofilament and predicts relapse-free progression in multiple sclerosis.Cell reports. Medicine · 2026Article
- [Recurrent hypoglycemia and the structure of the choroid plexus of the lateral ventricles of the rat brain].Problemy endokrinologii · 2026Article
- The choroid plexus water density.Magnetic resonance in medicine · 2026Article
- Choroid plexus volume variation in patients with gliomas, glioneuronal and neuronal tumors: Associations with tumor characteristics.PloS one · 2026Observational
- Variability in the circulation of cerebrospinal fluid: causes and clinical implications for intraventricular drug delivery.Frontiers in drug delivery · 2026Review
- Age-related differences in choroid plexus structural integrity are associated with changes in cognition.Fluids and barriers of the CNS · 2025Article
- The relationship between choroid plexus volume, DTI-ALPS index, kidney function, and amyloid pathology in alzheimer's disease.Neuroradiology · 2025Article
- Evidence for reduced choroid plexus volume in the aged brain.Fluids and barriers of the CNS · 2025Article
10 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The choroid plexus (CP) is an important cerebral structure involved in cerebrospinal fluid production and transport of solutes into the brain. Recent studies have uncovered the involvement of the CP in neurological disorders such as Alzheimer's disease and multiple sclerosis. However, our understanding of human age-related microstructural and functional changes in the CP with aging and neuropathology is limited. In this cross-sectional study, we investigated age and sex differences in the CP structure and function using advanced quantitative magnetic resonance imaging methodology in a large cohort (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.