Evidence map›Paper›PMID 34602981›Full record

ArticleFrontiers in cellular neuroscience2021

Glial Chloride Homeostasis Under Transient Ischemic Stress.

Miriam Engels, Manu Kalia, Sarah Rahmati, Laura Petersilie, Peter Kovermann, Michel J A M van Putten, Christine R Rose, Hil G E Meijer, Thomas Gensch, Christoph Fahlke

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 32 citations in OpenAlex.

  1. Overactive EAAT1 ClActa neuropathologica communications · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. In Vitro Effect of 9,9'-Norharmane Dimer against Herpes Simplex Viruses.International journal of molecular sciences · 2024
    Article
  8. Article
  9. The role ofJournal of pharmaceutical analysis · 2023
    Review
  10. Physiological roles of chloride ions in bodily and cellular functions.The journal of physiological sciences : JPS · 2023
    Review
  11. Article
  12. Article
  13. Article
  14. Modern Microscopic Approaches to Astrocytes.International journal of molecular sciences · 2023
    Review
  15. Review
  16. Frontiers in physiology · 2023
    Article
  17. Article
  18. Changes in Astroglial KInternational journal of molecular sciences · 2022
    Article
  19. Cellular Physiology and Pathophysiology of EAAT Anion Channels.Frontiers in cellular neuroscience · 2021
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Miriam EngelsInstitute of Biological Information Processing, Molekular-und Zellphysiologie (IBI-1), Forschungszentrum Jülich, Jülich, Germany.
Manu KaliaApplied Analysis, Department of Applied Mathematics, University of Twente, Enschede, Netherlands.
Sarah RahmatiInstitute of Biological Information Processing, Molekular-und Zellphysiologie (IBI-1), Forschungszentrum Jülich, Jülich, Germany.
Laura PetersilieInstitute of Neurobiology, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Peter KovermannInstitute of Biological Information Processing, Molekular-und Zellphysiologie (IBI-1), Forschungszentrum Jülich, Jülich, Germany.
Michel J A M van PuttenDepartment of Clinical Neurophysiology, University of Twente, Enschede, Netherlands.
Christine R RoseInstitute of Neurobiology, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Hil G E MeijerApplied Analysis, Department of Applied Mathematics, University of Twente, Enschede, Netherlands.
Thomas GenschInstitute of Biological Information Processing, Molekular-und Zellphysiologie (IBI-1), Forschungszentrum Jülich, Jülich, Germany.
Christoph FahlkeInstitute of Biological Information Processing, Molekular-und Zellphysiologie (IBI-1), Forschungszentrum Jülich, Jülich, Germany.
Forschungszentrum Jülich · DEHeinrich Heine University Düsseldorf · DEUniversity of Twente · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High water permeabilities permit rapid adjustments of glial volume upon changes in external and internal osmolarity, and pathologically altered intracellular chloride concentrations ([Cl

Indexed as

chemical stress mimicking ischemiaexcitatory amino acid transportersfluorescence lifetime imaging microscopyintracellular chloride concentrationsK-Cl cotransportersNa-K-2Cl cotransporter

Identifiers

PMID34602981
PMCPMC8481871
OpenAlexW3199535344

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.