Evidence map›Paper›PMID 34602857›Full record

ArticleMediators of inflammation2021

Effects of IQW and IRW on Inflammation and Gut Microbiota in ETEC-Induced Diarrhea.

Naiyuan Liu, Lingsi Zhou, Jun Fang, Hongmei Jiang, Gang Liu

Abstract read
In one paragraph

Article in Mediators of inflammation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. EnterotoxigenicTransboundary and emerging diseases · 2025
    Article
  4. Frontiers in veterinary science · 2024
    Article
  5. Article
  6. Article
  7. Effects ofAnimals : an open access journal from MDPI · 2022
    Article
  8. Comprehensive evaluation of the mechanism ofFrontiers in cellular and infection microbiology · 2022
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Naiyuan LiuCollege of Bioscience and Biotechnology, Hunan Agricultural University, Hunan Provincial Engineering Research Center of Applied Microbial Resources Development for Livestock and Poultry, Changsha, Hunan 410125, China.
Lingsi ZhouCollege of Bioscience and Biotechnology, Hunan Agricultural University, Hunan Provincial Engineering Research Center of Applied Microbial Resources Development for Livestock and Poultry, Changsha, Hunan 410125, China.
Jun FangCollege of Bioscience and Biotechnology, Hunan Agricultural University, Hunan Provincial Engineering Research Center of Applied Microbial Resources Development for Livestock and Poultry, Changsha, Hunan 410125, China.ORCID https://orcid.org/0000-0001-9532-8444
Hongmei JiangCollege of Bioscience and Biotechnology, Hunan Agricultural University, Hunan Provincial Engineering Research Center of Applied Microbial Resources Development for Livestock and Poultry, Changsha, Hunan 410125, China.
Gang LiuCollege of Bioscience and Biotechnology, Hunan Agricultural University, Hunan Provincial Engineering Research Center of Applied Microbial Resources Development for Livestock and Poultry, Changsha, Hunan 410125, China.ORCID https://orcid.org/0000-0002-9475-5134

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

methodsThe mice were randomly distributed into four groups: (a) control (CTRL) group, (b) ETEC group, (c) IQW-ETEC group, and (d) IRW-ETEC group. Villus length and crypt depth were measured after hematoxylin and eosin staining. The inflammatory reaction was analyzed via inflammatory cytokines (i.e., TNF-

resultsThe villus length decreased, the crypt depth decreased, and the expression of inflammatory cytokines (i.e., TNF-

conclusionThis study ascertained that the addition of IQW and IRW could alleviate jejunal inflammation and increase microbiota community diversity.

Indexed as

AnimalsColonCytokinesDiarrheaEnterotoxigenic Escherichia coliGastrointestinal MicrobiomeInflammationJejunumMaleMiceOligopeptidesCytokinesIRW peptideOligopeptides

Identifiers

PMID34602857
PMCPMC8486560

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.