Evidence map›Paper›PMID 34602807›Full record

SynthesisPsycho-oncology2021

A systematic review and meta-analysis of effects of psychosocial interventions on spiritual well-being in adults with cancer.

Laurie E McLouth, C Graham Ford, James E Pustejovsky, Crystal L Park, Allen C Sherman, Kelly Trevino, John M Salsman

Open access · greenAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Psycho-oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 3 pooled it
1.2field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 3 syntheses or guidelines pooled it, 33 citations in OpenAlex.

  1. Pooled it
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  3. Psychosocial interventions to improve quality of life in Hispanic cancer survivors: a meta-analysis.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2025
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  16. A single-arm pilot of MyInspiration: a novel digital resource to support spiritual needs of patients undergoing cancer-directed surgery.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 7 institutions in 1 country.

Laurie E McLouthDepartment of Behavioral Science, University of Kentucky College of Medicine, Lexington, Kentucky, USA.ORCID 0000-0002-4888-6520
C Graham FordDepartment of Psychology, University of New Mexico, Albuquerque, New Mexico, USA.
James E PustejovskyDepartment of Educational Psychology, University of Texas at Austin, Austin, Texas, USA.
Crystal L ParkDepartment of Psychological Sciences, University of Connecticut, Storrs, Connecticut, USA.ORCID 0000-0001-6572-7321
Allen C ShermanUniversity of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Kelly TrevinoMemorial Sloan Kettering Cancer Centre, New York City, New York, USA.
John M SalsmanWake Forest School of Medicine and the Wake Forest Baptist Comprehensive Cancer Centre, Winston-Salem, North Carolina, USA.
Atrium Health Wake Forest Baptist · USMemorial Sloan Kettering Cancer Center · USThe University of Texas at Austin · USUniversity of Arkansas for Medical Sciences · USUniversity of Connecticut · USUniversity of Kentucky · USUniversity of New Mexico · US

Funding

University of Kentucky Markey Cancer Center Support Grant ECIA SupplementP30CA177558 · NCI · UNIVERSITY OF KENTUCKY · PI Bernard Mark Evers · 2013 to 2026
$38.3M
Pilot CoreP30AG022845 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI Manney Carrington Reid, ELAINE WETHINGTON · 2003 to 2026
$15.2M
Postdoctoral Training Program in Cancer SurvivorshipR25CA122061 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI AVIS, NANCY E · 2008 to 2018
$3.8M
Meta-Analysis of Positive Psychology Interventions for Cancer (MAPPIC)R03CA184560 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI SALSMAN, JOHN · 2014 to 2015
$155k
NCI NIH HHS L30 CA231709NCI NIH HHS P30 CA177558NCI NIH HHS R03 CA184560NCI NIH HHS R25 CA122061NIA NIH HHS P30 AG022845
6 · The paper itself

Abstract

Objective: Spiritual well-being (SpWb) is an important dimension of health-related quality of life for many cancer patients. Accordingly, an increasing number of psychosocial intervention studies have included SpWb as a study endpoint, and may improve SpWb even if not designed explicitly to do so. This meta-analysis of randomized controlled trials (RCTs) evaluated effects of psychosocial interventions on SpWb in adults with cancer and tested potential moderators of intervention effects. Methods: Six literature databases were systematically searched to identify RCTs of psychosocial interventions in which SpWb was an outcome. Doctoral-level rater pairs extracted data using Covidence following Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines. Standard meta-analytic techniques were applied, including meta-regression with robust variance estimation and risk-of-bias sensitivity analysis. Results: Forty-one RCTs were identified, encompassing 88 treatment effects among 3883 survivors. Interventions were associated with significant improvements in SpWb ( Conclusions: Psychosocial interventions are associated with small-to-medium-sized effects on SpWb among cancer survivors. Future research should focus on conceptually coherent interventions explicitly targeting SpWb and evaluate interventions in samples that are diverse with respect to race and ethnicity, sex and cancer type.

Indexed as

Cancer SurvivorsNeoplasmsAdultHumansPsychosocial InterventionQuality of LifeSurvivorscancerinterventionsmeta-analysispsycho-oncologyrandomized controlled trialsspiritual well-being

Identifiers

PMID34602807
PMCPMC8485897
OpenAlexW3093400148

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.