Evidence map›Paper›PMID 34602775›Full record

ArticleBioinformation2021

Synonymous codon usage pattern among the S, M, and L segments in Crimean-congo hemorrhagic fever virus.

Mallikarjun S Beelagi, Sr Santosh Kumar, Uma Bharathi Indrabalan, Sharanagouda S Patil, Ashwini Prasad, K P Suresh, Shiva Prasad Kollur, Veeresh Santhebennur Jayappa, Siddappa B Kakkalameli, Chandrashekar Srinivasa and 2 more

Abstract read
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In one paragraph

Article in Bioinformation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Comparative analysis of codon usage patterns ofFrontiers in microbiology · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mallikarjun S BeelagiDepartment of Biotechnology and Bioinformatics, Faculty of Life Sciences, JSS Academy of Higher Education & Research, Mysuru-570015, India.
Sr Santosh KumarDepartment of Studies in Food Technology, Shivagangotri, Davangere University, Davangere Karnataka-577 007, India.
Uma Bharathi IndrabalanICAR-National Institute of Veterinary Epidemiology and Disease Informatics (NIVEDI), Yelahanka, Bengaluru-560064, India.
Sharanagouda S PatilICAR-National Institute of Veterinary Epidemiology and Disease Informatics (NIVEDI), Yelahanka, Bengaluru-560064, India.
Ashwini PrasadDepartment of Microbiology, Faculty of Life Sciences, JSS Academy of Higher Education & Research, Mysuru-570015, India.
K P SureshICAR-National Institute of Veterinary Epidemiology and Disease Informatics (NIVEDI), Yelahanka, Bengaluru-560064, India.
Shiva Prasad KollurDepartment of Sciences, Amrita School of Arts and Sciences, Mysuru, Amrita Vishwa Vidyapeetham, Karnataka - 570 026, India.
Veeresh Santhebennur JayappaDepartment of Studies in Environmental Science, Shivagangotri, Davangere University, Davangere Karnataka-577 007, India.
Siddappa B KakkalameliDepartment of Studies in Botany, Davangere University, Shivagangotri, Davangere Karnataka - 577 007, India.
Chandrashekar SrinivasaDepartment of Studies in Biotechnology, Davangere University, Shivagangotri, Davangere Karnataka-577 007, India.
Prabhakarareddy Anapalli VenkataravanaDepartment of Biotechnology and Bioinformatics, Faculty of Life Sciences, JSS Academy of Higher Education & Research, Mysuru-570015, India.
Chandan ShivamalluDepartment of Biotechnology and Bioinformatics, Faculty of Life Sciences, JSS Academy of Higher Education & Research, Mysuru-570015, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Crimean-Congo hemorrhagic fever (CCHF) virus is one among the major zoonosis viral diseases that use the Hyalomma ticks as their transmission vector to cause viral infection to the human and mammalian community. The fatality of infectious is high across the world especially in Africa, Asia, Middle East, and Europe. This study regarding codon usage bias of S, M, and L segments of the CCHF virus pertaining to the host Homo sapiens, reveals in-depth information about the evolutionary characteristics of CCHFV. Relative Synonymous Codon Usage (RSCU), Effective number of codons (ENC) were calculated, to determine the codon usage pattern in each segment. Correlation analysis between Codon adaptation index (CAI), GRAVY (Hydrophobicity), AROMO (Aromaticity), and nucleotide composition revealed bias in the codon usage pattern. There was no strong codon bias found among any segments of the CCHF virus, indicating both the factors i.e., natural selection and mutational pressure shapes the codon usage bias.

Indexed as

CCHF virusCodon usage biasHomo sapiensHost adaptationMutational pressureNatural selectionS, M, L segments

Identifiers

PMID34602775
PMCPMC8450151

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.