Evidence map›Paper›PMID 34602681›Full record

ReviewTrends in analytical chemistry : TRAC2021

Applications of scaffold-based advanced materials in biomedical sensing.

Roya Sarkhosh-Inanlou, Vahid Shafiei-Irannejad, Sajjad Azizi, Abolghasem Jouyban, Jafar Ezzati-Nazhad Dolatabadi, Ahmad Mobed, Bashir Adel, Jafar Soleymani, Michael R Hamblin

Abstract readReview
In one paragraph

Review in Trends in analytical chemistry : TRAC, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Roya Sarkhosh-InanlouCellular and Molecular Research Center, Cellular and Molecular Medicine Institute, Urmia University of Medical Sciences, Urmia, Iran.
Vahid Shafiei-IrannejadCellular and Molecular Research Center, Cellular and Molecular Medicine Institute, Urmia University of Medical Sciences, Urmia, Iran.
Sajjad AziziBiotechnology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Abolghasem JouybanPharmaceutical Analysis Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Jafar Ezzati-Nazhad DolatabadiDrug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Ahmad MobedAging Research Institute, Faculty of Medicine, Tabriz University of Medical Sciences, Iran.
Bashir AdelFood and Drug Safety Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Jafar SoleymaniPharmaceutical Analysis Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Michael R HamblinLaser Research Centre, Faculty of Health Science, University of Johannesburg, Doornfontein, Johannesburg, 2028, South Africa.

Funding

Photodynamic Therapy of Localized InfectionsR01AI050875 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI HAMBLIN, MICHAEL R · 2003 to 2017
$4.8M
Synergistic Photodynamic Therapy for Catherer-Associated Urinary Tract InfectionsR21AI121700 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI HAMBLIN, MICHAEL R · 2016 to 2017
$462k
NIAID NIH HHS R01 AI050875NIAID NIH HHS R21 AI121700
6 · The paper itself

Abstract

There have been many efforts to synthesize advanced materials that are capable of real-time specific recognition of a molecular target, and allow the quantification of a variety of biomolecules. Scaffold materials have a porous structure, with a high surface area and their intrinsic nanocavities can accommodate cells and macromolecules. The three-dimensional structure (3D) of scaffolds serves not only as a fibrous structure for cell adhesion and growth in tissue engineering, but can also provide the controlled release of drugs and other molecules for biomedical applications. There has been a limited number of reports on the use of scaffold materials in biomedical sensing applications. This review highlights the potential of scaffold materials in the improvement of sensing platforms and summarizes the progress in the application of novel scaffold-based materials as sensor, and discusses their advantages and limitations. Furthermore, the influence of the scaffold materials on the monitoring of infectious diseases such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and bacterial infections, was reviewed.

Indexed as

Advanced materialsBiomedical sensingDisease biomarkersInfectious diseasesScaffold materialsSevere acute respiratory syndrome coronavirus

Identifiers

PMID34602681
PMCPMC8474058

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.