Evidence map›Paper›PMID 34602669›Full record

ReviewRadiologia brasileira

Whole-body magnetic resonance imaging for the diagnosis of metastasis in children and adolescents: a systematic review and meta-analysis.

Simone Gianella Valduga, Gabriele Carra Forte, Ricardo Pessini Paganin, Diego Gomez Abreu, Tássia Machado Medeiros, Klaus Irion, Bruno Hochhegger, Rita Mattiello

Open access · diamondAbstract readReview
In one paragraph

Review in Radiologia brasileira. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Whole-Body MRI VersusCancers · 2026
    Article
  2. Article
  3. Post-Acquisition HyperpolarizedDiagnostics (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Simone Gianella ValdugaPontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, RS, Brazil.ORCID 0000-0001-9167-7284
Gabriele Carra FortePontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, RS, Brazil.ORCID 0000-0002-1480-8196
Ricardo Pessini PaganinPontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, RS, Brazil.ORCID 0000-0002-7156-0895
Diego Gomez AbreuUniversidad Industrial de Santander (UIS), Bucaramanga, Santander, Colombia.ORCID 0000-0002-4303-5225
Tássia Machado MedeirosPontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, RS, Brazil.ORCID 0000-0002-0536-2110
Klaus IrionThoracic Imaging DIIRM, Manchester University and Manchester University NHS Foundation Trust Department of Radiology, Manchester, UK.ORCID 0000-0002-7860-7879
Bruno HochheggerPontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, RS, Brazil.ORCID 0000-0003-1984-4636
Rita MattielloPontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, RS, Brazil.ORCID 0000-0002-0548-3342
Pontifícia Universidade Católica do Rio Grande do Sul · BRIndustrial University of Santander · COManchester University NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Whole-body magnetic resonance imaging (WB-MRI) is a noninvasive imaging method that can be used to diagnose and stage tumors, as well as to assess therapeutic responses in oncology. The objective of this meta-analysis was to evaluate the accuracy of WB-MRI for the diagnosis of metastases in pediatric patients. The following electronic databases were searched: Medline, Embase, Cochrane Central Register of Controlled Trials, Scientific Electronic Library Online, Latin-American and Caribbean Health Sciences Literature, Cumulative Index to Nursing and Allied Health Literature, Web of Science, and ClinicalTrials.gov. All of the selected studies included children and adolescents with histopathological confirmation of a primary tumor. Collectively, the studies included 118 patients ranging in age from 7 months to 19 years. The pooled sensitivity and specificity of WB-MRI were, respectively, 0.964 (95% CI: 0.944-0.978;

Indexed as

Magnetic resonance imaging/methodsMeta-analysisNeoplasms/diagnostic imagingPediatricsWhole body imaging/methods

Identifiers

PMID34602669
PMCPMC8475173
OpenAlexW3204731378

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.