Evidence map›Paper›PMID 34602094›Full record

ArticleJournal of medical case reports2021

Melkersson-Rosenthal syndrome in the context of sarcoidosis: a case report.

J Casper, S Mohammad-Khani, J J Schmidt, J T Kielstein, T Lenarz, H Haller, Annette D Wagner

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of medical case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

J Casper *Department of Nephrology and Hypertension, Hanover Medical School, Carl-Neuberg-Strasse 1, 30625, Hanover, Germany.
S Mohammad-Khani *Department of Nephrology and Hypertension, Hanover Medical School, Carl-Neuberg-Strasse 1, 30625, Hanover, Germany.
J J SchmidtDepartment of Nephrology and Hypertension, Hanover Medical School, Carl-Neuberg-Strasse 1, 30625, Hanover, Germany.
J T KielsteinDepartment of Nephrology, Städtisches Klinikum Braunschweig, Freisestraße 9-10, 38118, Brunswick, Germany.
T LenarzDepartment of Otolaryngology (ENT), Hanover Medical School, Carl-Neuberg-Strasse 1, 30625, Hanover, Germany.
H HallerDepartment of Nephrology and Hypertension, Hanover Medical School, Carl-Neuberg-Strasse 1, 30625, Hanover, Germany.
Annette D WagnerDepartment of Nephrology and Hypertension, Hanover Medical School, Carl-Neuberg-Strasse 1, 30625, Hanover, Germany. wagner.annette@mh-hannover.de.
Medizinische Hochschule Hannover · DEKlinikum Braunschweig · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMelkersson-Rosenthal syndrome is a rare disease characterized by the triad of recurrent orofacial swelling with facial paralysis and fissured dorsal tongue. Histologically, noncaseating granulomatous inflammation occurs that confirms the diagnosis. Overlaps between granulomatous diseases such as sarcoidosis and Crohn's disease are described. Systemic corticosteroid therapy is the treatment of choice for acute attacks. CASE PRESENTATION: We here present a case of a 59-year-old White woman suffering from Melkersson-Rosenthal syndrome with a past history of sarcoidosis on therapy with leflunomide in combination with low-dose tacrolimus successfully treated with the anti-leprosy drug clofazimine after failure of systemic steroid therapy.

conclusionsWe propose clofazimine as an alternative treatment in steroid-refractory cases.

Indexed as

Crohn DiseaseFacial ParalysisMelkersson-Rosenthal SyndromeSarcoidosisBehavior TherapyFemaleHumansMiddle AgedCase reportClofazimineMelkersson–Rosenthal syndrome

Identifiers

PMID34602094
PMCPMC8489098
OpenAlexW3202776386

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.