Evidence map›Paper›PMID 34601644›Full record

ArticleArchives of osteoporosis2021

Interactive effect of sarcopenia and falls on vertebral osteoporotic fracture in patients with rheumatoid arthritis.

Jing-Jing Tong, Sheng-Qian Xu, Jian-Xiong Wang, He-Xiang Zong, Yi-Ran Chu, Ke-Ming Chen, Yu-Zhu Teng

Abstract read
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Article in Archives of osteoporosis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jing-Jing TongDepartment of Rheumatology & Immunology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, Anhui, China.
Sheng-Qian XuDepartment of Rheumatology & Immunology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, Anhui, China. xsqian-1112@163.com.
Jian-Xiong WangDepartment of Rheumatology & Immunology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, Anhui, China.
He-Xiang ZongDepartment of Rheumatology & Immunology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, Anhui, China.
Yi-Ran ChuDepartment of Rheumatology & Immunology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, Anhui, China.
Ke-Ming ChenDepartment of Rheumatology & Immunology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, Anhui, China.
Yu-Zhu TengDepartment of Rheumatology & Immunology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, Anhui, China.
Anhui Medical University · CNFirst Affiliated Hospital of Anhui Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with rheumatoid arthritis (RA) had higher incidences of sarcopenia, falls, osteoporosis, and vertebral osteoporotic fractures (VOPF). Sarcopenia was associated with longer disease duration, higher disease activity, and more severe RA. The interactive effect of sarcopenia and falls was associated with a higher risk of VOPF in patients with RA. PURPOSE: Whether sarcopenia and falls are a risk factor for vertebral fracture in RA patients has not been demonstrated. This study aimed to explore the incidence of vertebral osteoporotic fracture (VOPF) and its relationship with sarcopenia and falls in RA patients.

methodsA total of 474 RA patients and 156 controls were enrolled in this study. Anteroposterior and lateral X-ray examinations of the vertebral column (T4-L4) were used for the semiquantitative assessment of VOPF. Bone mineral density was measured by dual-energy X-ray absorptiometry. Skeletal muscle mass was measured by direct segmental multifrequency bioelectrical impedance analysis (DSM-BIA method).

resultsRA patients had an increased risk of sarcopenia (62.4% vs 9.0%, x

conclusionsThe interactive effect of sarcopenia and falls is associated with a higher risk of VOPF in patients with RA.

Indexed as

Arthritis, RheumatoidOsteoporosisOsteoporotic FracturesSarcopeniaSpinal FracturesAgedBone DensityHumansRisk FactorsRheumatoid arthritisSarcopeniaVertebral osteoporotic fracture

Identifiers

PMID34601644
OpenAlexW3202585724

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.