ArticleClinical oral investigations2022
Stage II and stage III periodontitis clinical burdens of HIV-1 undergoing antiretroviral therapy.
Article in Clinical oral investigations, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 10 citations in OpenAlex.
- Cognitive impairment is associated with poorer oral health in people with HIV: evidence from a pilot study.Quintessence international (Berlin, Germany : 1985) · 2026Article
- Non-Surgical Periodontal Treatment Outcomes in Patients with HIV Under Antiretroviral Therapy: A Systematic Review.Journal of clinical medicine · 2026Review
- Interplay Between Oral Microbiota and Mouth Health in People Living With HIV Under Antiretroviral Therapy With or Without Periodontitis.International journal of dentistry · 2026Article
- A Crosstalk Between Periodontal Disease and Human Immunodeficiency Virus: Application of Artificial Intelligence and Machine Learning in Risk Assessment and Diagnosis-A Narrative Review.Dentistry journal · 2025Review
- Subgingival biofilm colonization by Candida albicans and Candida dubliniensis in patients living with HIV from Buenos Aires, Argentina.Acta odontologica latinoamericana : AOL · 2024Article
- Periodontal health in a large cohort of Ugandans living with HIV: a cross-sectional study.BMC oral health · 2024Article
- Periodontal health in a large cohort of Ugandansliving with HIV: A cross-sectional study.Research square · 2024Article
- Natural killer-like B cells are a distinct but infrequent innate immune cell subset modulated by SIV infection of rhesus macaques.PLoS pathogens · 2024Article
- HIV-Infected Individuals Do Not Present Significant Differences regarding Periodontal Status: A Systematic Review and Meta-Analysis.International journal of dentistry · 2024Article
- Factors Associated with Periodontitis in Patients with and without HIV.International journal of dentistry · 2023Article
Corrections and comments
- Erratum issued
Authors and funding
9 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe aim of this retrospective cross-sectional study was to estimate the association of HIV-1 infection under highly active antiretroviral treatment (HAART) on the clinical parameters of periodontitis. MATERIALS AND
methodsA total of 205 patients were divided in two groups: 74 HIV + and 131 HIV - . Periodontal probing depth (PPD), clinical attachment loss (CAL), bleeding on probing (BOP), and visible supragingival biofilm (VSB) were recorded. The association of HIV-1 infection with the presence of at least 3 sites with PPD ≥ 5 mm and/or CAL ≥ 4 mm in non-adjacent teeth was estimated using binary logistic regression models.
resultsThe variables HIV-1 infection (OR = 5.53, p < 0.0001, 95% CI: 2.45-13.64), age [range 35-50 years old (OR = 5.73, p < 0.0001, 95% CI: 2.49-13.20); > 50 years old (OR = 6.29, p = 0.002, 95% CI: 1.94-20.42)], and VSB (OR = 23.68, p < 0.0001, 95% CI: 8.07-69.53) showed a significant direct association with BOP outcome.
conclusionsHIV-1 infection under HAART did not have association with the presence of at least 3 sites with PPD ≥ 5 mm and/or CAL ≥ 4 mm. However, HIV patients on HAART had direct association of HIV-1 infection with BOP and an inverse association with PPD. CLINICAL RELEVANCE: These results support that monitoring gingival bleeding associated with oral prophylaxis would be beneficial in the prevention and management of periodontitis in HIV-1 patients on HAART.
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