ArticleNutrition & diabetes2021
Prediction of insulin treatment in women with gestational diabetes mellitus.
Article in Nutrition & diabetes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Prediction Models for Maternal and Offspring Short- and Long-Term Outcomes Following Gestational Diabetes: A Systematic Review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025Pooled it
- Clinical and biochemical factors associated with insulin therapy in gestational diabetes: The role of OGTT-based groups.Experimental physiology · 2026Observational
- The need for pharmacotherapy among patients with one or more elevations on glucose tolerance test.The Journal of clinical endocrinology and metabolism · 2026Article
- Women's experiences of navigating gestational diabetes in Denmark: a qualitative study of healthcare and self-care, with a focus on dietary education and delivery.BMC pregnancy and childbirth · 2026Article
- The use of machine learning to predict pharmacological therapy in gestational diabetes: A scoping review.Diabetic medicine : a journal of the British Diabetic Association · 2026Review
- Rate and Characteristics of Metformin Use in Gestational Diabetes.Obstetrics and gynecology international · 2026Article
- Precision Medicine and Shared Decision-Making to Advance Gestational Diabetes Management: Genetic, Metabolic, and Gut Microbiota Factors.Patient preference and adherence · 2026Review
- Comprehensive Review of Gestational Diabetes: Pathophysiology, Pharmacological Management and the Role of Pharmaceutical Care.Current drug safety · 2026Review
- Individual Prediction of Insulin Therapy in Gestational Diabetes: Development of a Risk Calculator Based on Real-World Data from the GestDiab Registry.Geburtshilfe und Frauenheilkunde · 2025Article
- Artificial Intelligence in Gestational Diabetes Care: A Systematic Review.Journal of diabetes science and technology · 2025Review
- Developing a Risk Stratification Tool to Predict Patients with Gestational Diabetes Mellitus at Risk of Insulin Treatment: A Cohort Study.Journal of personalized medicine · 2025Article
- Value-based evaluation of gestational diabetes mellitus care pathway redesign by using cost and outcome data.BMC pregnancy and childbirth · 2025Observational
- Application of Proteomics in Maternal and Neonatal Health: Advancements and Future Directions.Proteomics. Clinical applications · 2025Review
- Article
- Characterization of human placental fetal vessels in gestational diabetes mellitus.Pflugers Archiv : European journal of physiology · 2025Article
- Maternal and clinical predictors of insulin requirement in gestational diabetes mellitus (GDM): A cross-sectional study.Bioinformation · 2025Article
- Promoting breastfeeding in women with gestational diabetes mellitus in high-income settings: an integrative review.International breastfeeding journal · 2024Review
- The CHANGED Score-A New Tool for the Prediction of Insulin Dependency in Gestational Diabetes.Journal of clinical medicine · 2023Article
- On AI Approaches for Promoting Maternal and Neonatal Health in Low Resource Settings: A Review.Frontiers in public health · 2022Review
- Social Vulnerability and Initiation of Pharmacotherapy for Gestational Diabetes Mellitus in a Medicaid Population.Women's health issues : official publication of the Jacobs Institute of Women's HealthArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe identification of pregnant women with Gestational Diabetes Mellitus (GDM) who will require insulin therapy, may modify their management to closer monitoring and probable early interventions. The aim of the study was to develop a predictive model for the necessity of insulin treatment in women with GDM. MATERIALS AND
methodsThis was a prospective cohort study. Data from 775 women diagnosed with GDM per the IADPSG criteria were analyzed using logistic regression and a machine learning algorithm, the Classification and Regression Trees (CART). Potential predictors routinely recorded at follow-up visits were tested and used for the development of the model. The resultant model was externally validated using the data from two different perinatology clinics.
resultsPreconceptional maternal BMI and morning fasting blood glucose levels at baseline and at 1 h during an Oral Glucose Tolerance Test (OGTT) were independent significant predictors for the treatment modality of GDM. Baseline blood glucose greater than 98 mg/dl and preconceptional maternal Body Mass Index (BMI) between 26 and 31 kg/height
conclusionsA simple model based on maternal characteristics and the values of an OGTT can predict the need for insulin treatment with accuracy. Overweight women with an abnormal baseline blood glucose at OGTT are at high likelihood for insulin treatment. KEY MESSAGE: Fifteen to 30% of women with Gestational Diabetes Mellitus (GDM) require insulin therapy. Overweight women with baseline blood glucose greater than 98 mg/dl at OGTT are at increased risk for insulin treatment and close monitoring and increased physical exercise are required.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.