Evidence map›Paper›PMID 34601300›Full record

ArticleJournal of affective disorders2022

Pregnancy and postpartum psychiatric episodes in fathers: A population-based study on treatment incidence and prevalence.

Kathrine Bang Madsen, Merete Lund Mægbæk, Nete Stubkjær Thomsen, Xiaoqin Liu, Malin Eberhard-Gran, Alkistis Skalkidou, Veerle Bergink, Trine Munk-Olsen

Open access · goldAbstract read
In one paragraph

Article in Journal of affective disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 5 countries.

Kathrine Bang MadsenNational Centre for Register-based Research, Business and Social Sciences, Aarhus University, Fuglesangs Allé 26, Building R, Aarhus 8210, Denmark; iPSYCH, the Lundbeck Foundation Initiative for Integrative Psychiatric Research, Denmark. Electronic address: kathrine.bang@econ.au.dk.
Merete Lund MægbækNational Centre for Register-based Research, Business and Social Sciences, Aarhus University, Fuglesangs Allé 26, Building R, Aarhus 8210, Denmark; iPSYCH, the Lundbeck Foundation Initiative for Integrative Psychiatric Research, Denmark.
Nete Stubkjær ThomsenNational Centre for Register-based Research, Business and Social Sciences, Aarhus University, Fuglesangs Allé 26, Building R, Aarhus 8210, Denmark; iPSYCH, the Lundbeck Foundation Initiative for Integrative Psychiatric Research, Denmark.
Xiaoqin LiuNational Centre for Register-based Research, Business and Social Sciences, Aarhus University, Fuglesangs Allé 26, Building R, Aarhus 8210, Denmark; iPSYCH, the Lundbeck Foundation Initiative for Integrative Psychiatric Research, Denmark.
Malin Eberhard-GranNorwegian Research Centre for Women's Health, Women and Children's Division, Oslo University Hospital, Rikshospitalet, Oslo Norway; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Alkistis SkalkidouDepartment of Women's and Children's Health, Uppsala University, Sweden.
Veerle BerginkDepartment of Psychiatry and Department of Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai, NY, USA; Department of Psychiatry, Rotterdam, Erasmus MC, the Netherlands.
Trine Munk-OlsenNational Centre for Register-based Research, Business and Social Sciences, Aarhus University, Fuglesangs Allé 26, Building R, Aarhus 8210, Denmark; iPSYCH, the Lundbeck Foundation Initiative for Integrative Psychiatric Research, Denmark.
Aarhus University · DKErasmus MC · NLOslo University Hospital · NOUppsala University · SE

Funding

Relapse risk after Discontinuation of Antidepressants during Pregnancy (R-DAP study)R01MH122869 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Veerle Bergink · 2020 to 2026
$4.3M
NIMH NIH HHS R01 MH122869
6 · The paper itself

Abstract

backgroundFor women, the perinatal period confers an increased risk of severe psychiatric disorders, but similar evidence for fathers is lacking. We examined rates of first-time and recurrent psychiatric disorders in men before and after becoming fathers.

methodsA descriptive prospective study design was applied using information from the Danish National registers. Perinatal psychiatric episodes were assessed as incidence of first-time and prevalence (including recurrence) of recorded in- or outpatient admissions for any mental disorder and redeemed prescriptions for psychotropic medication in fathers to children born from January 1, 1998 until December 31, 2015.

resultsWe identified 929,415 births and 543,555 unique fathers. Incidence and prevalence proportions for paternal psychiatric in- and outpatient episodes showed an increasing trend over the perinatal period and were marginally higher postpartum compared to pregnancy; e.g., median incidence proportion for inpatient treatment during pregnancy was 0.07 (95% CI: 0.04; 0.07) and 0.10 (95% CI: 0.08; 0.11) postpartum per 1000 births. No difference between the periods was found for incidence of prescriptions for psychotropic medication. Psychiatric disorders in expecting and new fathers were mainly treated in primary care with cumulative incidence of prescriptions for psychotropic medication of 14.56 per 1000 births during the first year of fatherhood. LIMITATIONS: We only capture fathers who actively sought and received treatment, and we consequently underestimate milder psychiatric episodes in expecting and new fathers.

conclusionBecoming a father did not appear to trigger a substantially increased risk of severe psychiatric disorders, as it has been observed for new mothers.

Indexed as

FathersPostpartum PeriodChildFemaleHumansIncidenceMalePregnancyPrevalenceProspective StudiesRisk FactorsFathersIncidencePerinatal psychiatric episodesPostpartum depressionPrevalenceRegister-based population study

Identifiers

PMID34601300
PMCPMC8595874
OpenAlexW3199878408

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.