SynthesisJournal of affective disorders2022
A systematic review and meta-analysis of longitudinal cohort studies comparing mental health before versus during the COVID-19 pandemic in 2020.
Synthesis in Journal of affective disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 579 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
579 citing papers in PubMed, 6 syntheses or guidelines pooled it, 1,074 citations in OpenAlex.
- Impact of educational agents on student's learning outcomes: a meta-analysis.Frontiers in psychology · 2026Pooled it
- Temporal patterns of suicidal ideation prevalence during the COVID-19 pandemic: a systematic review and meta-analysis of cross-sectional and longitudinal studies.Epidemiology and psychiatric sciences · 2025Pooled it
- Research Review: The impact of the COVID-19 pandemic on the mental health of children and young people with pre-existing mental health and neurodevelopmental conditions - a systematic review and meta-analysis of longitudinal studies.Journal of child psychology and psychiatry, and allied disciplines · 2025Pooled it
- Prevalence of anxiety, depression, and post-traumatic stress disorder among paramedic students: a systematic review and meta-analysis.Social psychiatry and psychiatric epidemiology · 2025Pooled it
- Pooled it
- Changes in the prevalence of mental health problems during the first year of the pandemic: a systematic review and dose-response meta-analysis.BMJ mental health · 2024Pooled it
- Effectiveness of cognitive remediation in subjects with major depressive disorder: A multicenter randomized controlled study in a real-world setting.European psychiatry : the journal of the Association of European Psychiatrists · 2025Trial
- A Longitudinal RCT on the Effectiveness of a Psychological Intervention for Hospital Healthcare Workers During the COVID-19 Pandemic: What We Learned to Date.Journal of clinical psychology in medical settings · 2025Trial
- Article
- Article
- Leveraging Google location history data to assess the impact of activities, locations, and time spent in green space on mental health during the COVID-19 pandemic.American journal of epidemiology · 2026Article
- From depression to bone health: examining the skeletal effects of classical and rapid-acting antidepressants.The international journal of neuropsychopharmacology · 2026Review
- Harmonising Depression and Anxiety Measures Across International Cohorts: A Framework Validated Using Measurement Invariance.International journal of methods in psychiatric research · 2026Article
- Trajectories of child emotional and behavioural difficulties before and during the COVID-19 pandemic in a longitudinal UK cohort.JCPP advances · 2026Article
- Prevalence and Correlates of Depressive Symptoms in Canada During the COVID-19 Pandemic: A Systematic Review and Meta-Analysis Based on 144 Studies Including 406,043 Participants: Prévalence et corrélats des symptômes dépressifs au Canada pendant la pandémie de COVID-19 : revue systématique et méta-analyse de 144 études comprenant 406 043 participants.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2026Review
- Predicting Mental Health Risk from Early-Life Adversity: A Population-Based Study of Canadian Adults: Prédiction du risque pour la santé mentale liée à l'adversité en début de vie : Étude fondée sur une population d'adultes canadiens.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2026Article
- Psychosocial stress from pre- to post-pandemic times: latent class mixed model analysis using data from a German cohort.Social psychiatry and psychiatric epidemiology · 2026Article
- Dissociative symptoms during the SARS-CoV-2 pandemic situation in mental health patients.Borderline personality disorder and emotion dysregulation · 2026Article
- Methodological strengths and weaknesses of nature based intervention: a systematic review.Cognitive processing · 2026Review
- Trends and patterns of medical stimulant use by US adults.Molecular psychiatry · 2026Article
519 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIncreases in mental health problems have been observed during the COVID-19 pandemic. The objectives were to examine the extent to which mental health symptoms changed during the pandemic in 2020, whether changes were persistent or short lived, and if changes were symptom specific.
methodsSystematic review and meta-analysis of longitudinal cohort studies examining changes in mental health among the same group of participants before vs. during the pandemic in 2020.
resultsSixty-five studies were included. Compared to pre-pandemic outbreak, there was an overall increase in mental health symptoms observed during March-April 2020 (SMC = .102 [95% CI: .026 to .192]) that significantly declined over time and became non-significant (May-July SMC = .067 [95% CI: -.022 to .157]. Compared to measures of anxiety (SMC = 0.13, p = 0.02) and general mental health (SMC = -.03, p = 0.65), increases in depression and mood disorder symptoms tended to be larger and remained significantly elevated in May-July [0.20, 95% CI: .099 to .302]. In primary analyses increases were most pronounced among samples with physical health conditions and there was no evidence of any change in symptoms among samples with a pre-existing mental health condition. LIMITATIONS: There was a high degree of unexplained heterogeneity observed (I
conclusionsThere was a small increase in mental health symptoms soon after the outbreak of the COVID-19 pandemic that decreased and was comparable to pre-pandemic levels by mid-2020 among most population sub-groups and symptom types.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.