Evidence map›Paper›PMID 34600281›Full record

ArticleEpilepsy & behavior : E&B2021

A ketogenic diet protects DBA/1 and Scn1a

Megan S Crotts, YuJaung Kim, Eduardo Bravo, George B Richerson, Frida A Teran

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Epilepsy & behavior : E&B, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Sudden unexpected death in epilepsy.Current opinion in neurology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Megan S CrottsDepartment of Neurology, University of Iowa, Iowa City, IA 52242, United States; Iowa Neuroscience Institute, University of Iowa, Iowa City, IA 52242, United States.
YuJaung KimDepartment of Neurology, University of Iowa, Iowa City, IA 52242, United States.
Eduardo BravoDepartment of Neurology, University of Iowa, Iowa City, IA 52242, United States.
George B RichersonDepartment of Neurology, University of Iowa, Iowa City, IA 52242, United States; Iowa Neuroscience Institute, University of Iowa, Iowa City, IA 52242, United States; Department of Molecular Physiology & Biophysics, University of Iowa, Iowa City, IA 52242, United States; Neurology, Veterans Affairs Medical Center, Iowa City, IA 52242, United States.
Frida A TeranDepartment of Neurology, University of Iowa, Iowa City, IA 52242, United States; Iowa Neuroscience Institute, University of Iowa, Iowa City, IA 52242, United States; Medical Scientist Training Program, University of Iowa, Iowa City, IA 52242, United States. Electronic address: frida-teran@uiowa.edu.
University of Iowa · US

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007337 · NIGMS · UNIVERSITY OF IOWA · PI GEYER, PAMELA K., LENTZ, STEVEN R · 1985 to 2020
$15.9M
SUDEP Translational Research Alliance (SUTRA): Autonomic and Imaging Biomarkers of SUDEP; SUTRA 3 of 7U01NS090407 · NINDS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI DIEHL, BEATE, HARPER, RONALD MARVEN · 2014 to 2018
$7.3M
SUDEP Research Alliance: Respiratory and Arousal Mechanisms, Application 5 of 7U01NS090414 · NINDS · UNIVERSITY OF IOWA · PI RICHERSON, GEORGE B · 2014 to 2018
$3.3M
Prevention of SUDEP by milk whey: Role of CO2 chemoreception and serotoninR01NS123155 · NINDS · UNIVERSITY OF IOWA · PI RICHERSON, GEORGE B · 2021 to 2025
$2.9M
A novel dietary therapy for epilepsy: potential mechanisms of actionF31NS110333 · NINDS · UNIVERSITY OF IOWA · PI TERAN, FRIDA ANGELINA · 2018 to 2021
$153k
NINDS NIH HHS F31 NS110333NINDS NIH HHS R01 NS123155NINDS NIH HHS U01 NS090407NINDS NIH HHS U01 NS090414
6 · The paper itself

Abstract

Patients with uncontrolled epilepsy have a high risk of sudden unexpected death in epilepsy (SUDEP). Seizure-induced respiratory arrest (S-IRA) is thought to be the determining cause of death in many cases of SUDEP. The goal of the present study was to use Scn1a

Indexed as

ApneaDietary therapiesEpilepsySUDEP

Identifiers

PMID34600281
PMCPMC8960470
OpenAlexW3203605434

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.