Evidence map›Paper›PMID 34600165›Full record

ReviewCurrent opinion in chemical biology2021

Recent advances in the mass spectrometric profiling of bacterial lipids.

Neetika Jaisinghani, Jessica C Seeliger

Abstract readReview
In one paragraph

Review in Current opinion in chemical biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Neetika JaisinghaniDepartment of Pharmacological Sciences, Stony Brook University, Stony Brook, NY, 11794, USA.
Jessica C SeeligerDepartment of Pharmacological Sciences, Stony Brook University, Stony Brook, NY, 11794, USA. Electronic address: jessica.seeliger@stonybrook.edu.

Funding

Chemical Biology Training InterfaceT32GM136572 · NIGMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI ELIZABETH M BOON, Jessica Chuang Seeliger · 2020 to 2026
$2.9M
Cell Envelope Biogenesis in Mycobacterium tuberculosisR01AI141513 · NIAID · STATE UNIVERSITY NEW YORK STONY BROOK · PI SEELIGER, JESSICA CHUANG · 2018 to 2022
$1.8M
NIAID NIH HHS R01 AI141513NIGMS NIH HHS T32 GM136572
6 · The paper itself

Abstract

Exploring the lipids of bacteria presents a predicament that may not be broadly recognized in a field dominated by the biology and biochemistry of eukaryotic - and especially, mammalian - lipids. Bacteria make multifarious metabolites that contain fatty acyl chains of unusual length and unsaturation attached to assorted headgroups, including sugars and fatty alcohols. Lipid profiling approaches developed for eukaryotic lipids often fail to detect, resolve, or identify bacterial lipids due to their wide range of polarities (including very hydrophobic species) and diverse positional and stereochemical variations. Global lipid profiling, or lipidomics, of bacteria has thus developed as a separate mission with methodological and scientific considerations tailored to the biology of these organisms. In this review, we summarize findings primarily from the last three years that exemplify recent advances and continuing challenges to learning about bacterial lipids.

Indexed as

BacteriaLipidomicsLipidsMass SpectrometryLipidsBacteriaLipidomicsLipidsMass spectrometry

Identifiers

PMID34600165
PMCPMC11628404

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.