SynthesisNeuroImage2021
Multi-band FMRI compromises detection of mesolimbic reward responses.
Synthesis in NeuroImage, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Relating Functional Connectivity and Alcohol Use Disorder: A Systematic Review and Derivation of Relevance Maps for Regions and Connections.Human brain mapping · 2025Pooled it
- Common and Distinct Neural Substrates for Approach- and Avoidance-Motivated Actions.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Altered reward-related resting-state network properties in adolescent cannabis use and depression.Progress in neuro-psychopharmacology & biological psychiatry · 2026Article
- Article
- Precision Imaging for Intraindividual Investigation of the Reward Response.Human brain mapping · 2026Article
- Article
- Reduced neural specificity for a romantic partner in the nucleus accumbens over relationship duration.Social cognitive and affective neuroscience · 2026Article
- Prior novelty invigorates future mesolimbic target detection.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Auditory and Visual Thalamocortical Connectivity Alterations in Unmedicated People With Schizophrenia: An Individualized Sensory Thalamic Localization and Resting-State Functional Connectivity Study.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2025Article
- Brain activity explains message effectiveness: A mega-analysis of 16 neuroimaging studies.PNAS nexus · 2025Article
- Prior Novelty Invigorates Future Mesolimbic Target Detection.bioRxiv : the preprint server for biology · 2025Article
- The Impact of Multiband and In-Plane Acceleration on White Matter Microstructure Analysis.Human brain mapping · 2025Article
- Deconstructing neural predictors of risky choice.PNAS nexus · 2025Article
- Baseline physical activity moderates brain-behaviour relationships in response to framed health messages.Social cognitive and affective neuroscience · 2025Article
- Neural mechanisms underlying reward processing and social cognition: A replication study with a Japanese sample.PloS one · 2025Article
- Unintended bias in the pursuit of collinearity solutions in fMRI analysis.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Pattern separation involves regions beyond the hippocampus in non-demented elderly individuals: A 7T object lure task fMRI study.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Brain encoding during perceived control as a prospective predictor of improvement in quality of life.Social cognitive and affective neuroscience · 2024Article
- The magic, memory, and curiosity fMRI dataset of people viewing magic tricks.Scientific data · 2024Article
- Structure-function coupling in macroscale human brain networks.Nature reviews. Neuroscience · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Recent innovations in Functional Magnetic Resonance Imaging (FMRI) have sped data collection by enabling simultaneous scans of neural activity in multiple brain locations, but have these innovations come at a cost? In a meta-analysis and preregistered direct comparison of original data, we examined whether acquiring FMRI data with multi-band versus single-band scanning protocols might compromise detection of mesolimbic activity during reward processing. Meta-analytic results (n = 44 studies; cumulative n = 5005 subjects) indicated that relative to single-band scans, multi-band scans showed significantly decreased effect sizes for reward anticipation in the Nucleus Accumbens (NAcc) by more than half. Direct within-subject comparison of single-band versus multi-band scanning data (multi-band factors = 4 and 8; n = 12 subjects) acquired during repeated administration of the Monetary Incentive Delay task indicated that reductions in temporal signal-to-noise ratio could account for compromised detection of task-related responses in mesolimbic regions (i.e., the NAcc). Together, these findings imply that researchers should opt for single-band over multi-band scanning protocols when probing mesolimbic responses with FMRI. The findings also have implications for inferring mesolimbic activity during related tasks and rest, for summarizing historical results, and for using neuroimaging data to track individual differences in reward-related brain activity.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.