Evidence map›Paper›PMID 34599630›Full record

ArticleJournal of cosmetic dermatology2021

The effect of COVID-19 on patients with chronic spontaneous urticaria treated with omalizumab and antihistamines: A cross-sectional, comparative study.

Ecem Bostan, Fethi Zaid, Aysen Karaduman, Sibel Dogan, Duygu Gulseren, Basak Yalici-Armagan, Neslihan Akdogan, Sibel Ersoy-Evans, Gonca Elcin

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in Journal of cosmetic dermatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
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  4. The effect of COVID-19 on patients recieving omalizumab treatment.Revue francaise d'allergologie (2009) · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Ecem BostanDepartment of Dermatology and Venereology, Faculty of Medicine, Hacettepe University, Ankara, Turkey.ORCID https://orcid.org/0000-0002-8296-4836
Fethi ZaidDepartment of Dermatology and Venereology, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
Aysen KaradumanDepartment of Dermatology and Venereology, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
Sibel DoganDepartment of Dermatology and Venereology, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
Duygu GulserenDepartment of Dermatology and Venereology, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
Basak Yalici-ArmaganDepartment of Dermatology and Venereology, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
Neslihan AkdoganDepartment of Dermatology and Venereology, Faculty of Medicine, Hacettepe University, Ankara, Turkey.ORCID https://orcid.org/0000-0002-1137-5399
Sibel Ersoy-EvansDepartment of Dermatology and Venereology, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
Gonca ElcinDepartment of Dermatology and Venereology, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
Hacettepe University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionChronic spontaneous urticaria (CSU) is defined as recurrent attacks of urticaria present for more than six weeks. The monoclonal anti-immunoglobulin E antibody, omalizumab, was approved for the treatment of CSU in patients who remain refractory to H1-antihistamines. Biologic agents are shown not to increase the risk of COVID-19 infection in different studies.

objectiveIn the present study, we aimed to determine the prevalance of COVID-19 infection in relation to the age, gender, presence of other comorbidities, and treatment given for CSU.

methodsWe conducted a descriptive cross-sectional study of 233 patients diagnosed with CSU in a tertiary referral hospital. Demographical data, treatment given for CSU, the presence of COVID-19-related symptoms, history of close contact to a person with COVID-19 and COVID-19 real-time polymerase chain reaction (RT-PCR) results were determined via a telephone survey and checked from medical data records.

resultsOne hundred sixty patients were female; whereas 73 were male. The mean age was 44.76. Out of 233 patients with chronic urticaria, 125 had symptoms related to COVID-19 infection. RT-PCR testing for COVID-19 was performed in 156 patients. Of 156 patients with COVID-19 RT-PCR test, RT-PCR result was positive in 15 cases.

conclusionsNo statistically significant relationship was found between COVID-19 RT-PCR positivity and the type of treatment administered for chronic urticaria when the patients are divided into omalizumab ± oral antihistamines and only oral antihistamines treatment groups (p = 0.150). Omalizumab seems to be safe in the era of COVID-19.

Indexed as

Anti-Allergic AgentsChronic UrticariaCOVID-19Histamine AntagonistsOmalizumabAdultChronic DiseaseCOVID-19 TestingCross-Sectional StudiesFemaleHumansMaleTreatment OutcomeAnti-Allergic AgentsHistamine AntagonistsOmalizumabchronic urticariaCOVID-19omalizumab

Identifiers

PMID34599630
PMCPMC8661558
OpenAlexW3204884223

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.