Evidence map›Paper›PMID 34599529›Full record

ArticleJournal of cardiac surgery2021

Successful use of Impella 5.5 to manage cardiogenic shock complicated by COVID-19.

Shant H Mahrokhian, Taylor Nordan, Jamel P Ortoleva, Frederick C Cobey, Frederick Y Chen, Navin K Kapur, Masashi Kawabori

Open access · greenAbstract readCase Reports
In one paragraph

Article in Journal of cardiac surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Shant H MahrokhianDivision of Cardiac Surgery, CardioVascular Center, Tufts Medical Center, Boston, Massachusetts, USA.ORCID http://orcid.org/0000-0003-4094-8739
Taylor NordanDivision of Cardiac Surgery, CardioVascular Center, Tufts Medical Center, Boston, Massachusetts, USA.
Jamel P OrtolevaDivision of Anesthesiology and Perioperative Medicine, Division of Cardiac Surgery, CardioVascular Center, Tufts Medical Center, Boston, Massachusetts, USA.
Frederick C CobeyDivision of Anesthesiology and Perioperative Medicine, Division of Cardiac Surgery, CardioVascular Center, Tufts Medical Center, Boston, Massachusetts, USA.
Frederick Y ChenDivision of Cardiac Surgery, CardioVascular Center, Tufts Medical Center, Boston, Massachusetts, USA.
Navin K KapurDivision of Cardiology, CardioVascular Center, Tufts Medical Center, Boston, Massachusetts, USA.
Masashi KawaboriDivision of Cardiac Surgery, CardioVascular Center, Tufts Medical Center, Boston, Massachusetts, USA.ORCID http://orcid.org/0000-0002-3580-5664
Tufts Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute decompensated heart failure in patients with coronavirus disease 2019 (COVID-19) is becoming increasingly common.

aimsIn this case report, we describe the successful use of an Impella 5.5 (Abiomed) to treat cardiogenic shock refractory to inotropic therapy. MATERIALS &

methodsTransthoracic and transesophageal echocardiography confirmed severely diminished left ventricular ejection fraction and a reverse-transcription polymerase chain reaction test revealed that the patient was COVID-19 positive during his hospital admission.

resultsFollowing initiation of inotropic therapy, we placed an Impella 5.5 for further cardiac support. The patient's LVEF and cardiac index improved after 21 days on the Impella 5.5 and was maintained following explant. DISCUSSION &

conclusionThe findings reported here demonstrate successful use of an Impella 5.5 to improve native heart function in refractory cardiogenic shock and further indicate its use as an option for those in acute decompensated heart failure who have tested positive for COVID-19 infection.

Indexed as

COVID-19Heart-Assist DevicesHumansRetrospective StudiesSARS-CoV-2Shock, CardiogenicStroke VolumeTreatment OutcomeVentricular Function, LeftCOVID-19heart failureImpella 5.5

Identifiers

PMID34599529
PMCPMC8661959
OpenAlexW3202179998

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.