ArticleJournal of neuro-oncology2021
Tumor location-based classification of surgery-related language impairments in patients with glioma.
Article in Journal of neuro-oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT05143775 (Strategic Intervention on Preserving Language Function During Awake Craniotomy for Glioma Resection), which is not on this map. Cited by 12 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Strategic Intervention on Preserving Language Function During Awake Craniotomy for Glioma Resection
Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.
- Influence of supratotal resection on overall survival and progression of tumor in gliomas grade 2 and 3: a systematic review and meta-analysis.Neurosurgical review · 2025Pooled it
- An update on tests used for intraoperative monitoring of cognition during awake craniotomy.Acta neurochirurgica · 2024Pooled it
- Awake Craniotomy for Eloquent Region Glioblastoma Classified by Tumor Location-A Retrospective and Prospective Cohort Study.CNS neuroscience & therapeutics · 2026Trial
- Speech-Language Pathology-Related Disorders in Adults with Brain Tumours: A Narrative Review.Biomedicines · 2026Review
- Language Processing in Posterior Fossa Tumour Patients: Psycholinguistic Insights into the Word-Finding Ability.Cerebellum (London, England) · 2026Article
- Tracing the language: enhancing neurosurgery with structural connectomics for prediction of language function preservation.European radiology · 2024Article
- Structural connectome combining DTI features predicts postoperative language decline and its recovery in glioma patients.European radiology · 2024Article
- The arcuate fasciculus: Combining structure and function into surgical considerations.Brain and behavior · 2023Review
- The impact of patient factors and tumor characteristics on language neuroplasticity in left hemispheric diffuse gliomas prior to surgical resection.Journal of neuro-oncology · 2023Article
- Decreasing distance from tumor to the language network causes language deficit.Human brain mapping · 2023Article
- Clinical management and survival outcomes of patients with different molecular subtypes of diffuse gliomas in China (2011-2017): a multicenter retrospective study from CGGA.Cancer biology & medicine · 2022Article
- Contralesional Cortical and Network Features Associated with Preoperative Language Deficit in Glioma Patients.Cancers · 2022Article
Corrections and comments
- Erratum issued
Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
introductionMany patients with glioma experience surgery-related language impairment. This study developed a classification system to predict postoperative language prognosis.
methodsSixty-eight patients were retrospectively reviewed. Based on their location, tumors were subtyped as follows: (I) inferior frontal lobe or precentral gyrus; (II) posterior central gyrus or supramarginal gyrus (above the lateral fissure level); (III) posterior region of the superior or middle temporal gyri or supramarginal gyrus (below the lateral fissure level); and (IV) insular lobe. The distance from the tumor to the superior longitudinal fasciculus/arcuate fasciculus was calculated. The recovery of language function was assessed using the Western Aphasia Battery before surgery, and a comprehensive language test was conducted on the day of surgery; 3, 7, and 14 days after surgery. Our follow-up information of was the comprehensive language test from telephone interviews in 3 months after surgery.
resultsThirty-three patients experienced transient language impairment within 1 week of surgery. Fourteen patients had permanent language impairment. Type II tumors, shorter distance from the tumor to the posterior superior longitudinal fasciculus/arcuate fasciculus, and isocitrate dehydrogenase mutations were risk factors for surgery-related language impairment. Regarding the presence or absence of permanent surgery-related language impairments, the cut-off distance between the tumor and posterior superior longitudinal fasciculus/arcuate fasciculus was 2.75 mm.
conclusionsAccording to our classification, patients with type II tumors had the worst language prognosis and longest recovery time. Our classification, based on tumor location, can reliably predict postoperative language status and may be used to guide tumor resection.
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