Evidence map›Paper›PMID 34599425›Full record

ReviewCurrent cardiology reports2021

Cusp Overlap Technique: Should It Become the Standard Implantation Technique for Self-expanding Valves?

Aditya Sengupta, Sophia L Alexis, Timothy Lee, Syed Zaid, Parasuram M Krishnamoorthy, Sahil Khera, Stamatios Lerakis, Malcolm Anastasius, George D Dangas, Samin K Sharma and 2 more

Abstract readReview
In one paragraph

Review in Current cardiology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. The Verification of Co-Axiality of the Three Self-Expanding Transcatheter Aortic Valve Systems According to the Difference in Shaft Spine.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026
    Article
  6. Short-Term Outcomes of ACURATE neo2.Structural heart : the journal of the Heart Team · 2024
    Review
  7. Review
  8. Article
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Aditya SenguptaDepartment of Cardiovascular Surgery, The Mount Sinai Hospital, New York, NY, USA.ORCID http://orcid.org/0000-0001-9217-9252
Sophia L AlexisDepartment of Cardiovascular Surgery, The Mount Sinai Hospital, New York, NY, USA.
Timothy LeeDepartment of Cardiovascular Surgery, The Mount Sinai Hospital, New York, NY, USA.
Syed ZaidDivision of Cardiology, Westchester Medical Center, Valhalla, NY, USA.
Parasuram M KrishnamoorthyZena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Sahil KheraZena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Stamatios LerakisZena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Malcolm AnastasiusZena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
George D DangasZena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Samin K SharmaZena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Annapoorna S KiniZena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Gilbert H L TangDepartment of Cardiovascular Surgery, The Mount Sinai Hospital, New York, NY, USA. gilbert.tang@mountsinai.org.

Funding

Toward Therapeutic Manipulation of Endothelial to Mesenchymal TransitionR01HL130423 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI ISHIKAWA, KIYOTAKE, KOVACIC, JASON CIRIL · 2016 to 2020
$2.1M
NHLBI NIH HHS R01 HL130423
6 · The paper itself

Abstract

purpose of reviewAccurate imaging of the aortic root during valve implantation is crucial for proper prosthesis positioning during TAVR. The purpose of this review was to determine if routine use of the cusp-overlap view should be adopted for self-expanding valves. RECENT

findingsThe use of the cusp-overlap view with the Evolut, Portico, ACURATE neo/neo2, and JenaValve systems is associated with lower post-procedural new permanent pacemaker implantation rates when compared with the standard 3-cusp view, presumably due to more precise valve implantation relative to the conduction system by the non-coronary cusp. By elongating the left ventricular outflow tract and accentuating the right-non commissure in the center of the fluoroscopic view, the cusp-overlap technique allows operators to more precisely control the prosthesis implant depth during self-expanding valve deployment. While the early experience with this approach in Evolut TAVR has been promising, the results of larger studies with longer follow-up across multiple self-expanding systems are warranted.

Indexed as

Aortic Valve StenosisHeart Valve ProsthesisTranscatheter Aortic Valve ReplacementAortic ValveHumansProsthesis DesignTreatment OutcomeAortic stenosisCommissural alignmentCusp-overlapPermanent pacemaker implantationSelf-expandingTranscatheter aortic valve replacement

Identifiers

PMID34599425
PMCPMC8845572

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.