ReviewCurrent cardiology reports2021
The Global Impact of Rheumatic Heart Disease.
Review in Current cardiology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- Pooled it
- Current Situation of Acute Rheumatic Fever and Rheumatic Heart Disease in Latin America and the Caribbean: A Systematic Review.Global heart · 2022Pooled it
- Inhibitors of GapN-dependent NADPH supply as potential lead compounds for novel therapeutics againstVirulence · 2026Article
- Survival and mortality predictors among adults with rheumatic heart disease in ethiopia: a 10-year retrospective cohort study.BMC cardiovascular disorders · 2026Article
- An Integrative Review of the Cardiovascular Disease Spectrum: Integrating Multi-Omics and Artificial Intelligence for Precision Cardiology.Diseases (Basel, Switzerland) · 2026Review
- Integrating equity and justice in rheumatic heart disease policy: addressing reproductive health challenges.International journal of public health · 2026Article
- Global burden of rheumatic vs non-rheumatic valvular heart disease, 1990-2021: a systematic analysis of the global burden of disease study.Clinical rheumatology · 2025Article
- Practice and clinical outcomes of valvular surgery for rheumatic heart disease in africa: a scoping review.Journal of cardiothoracic surgery · 2025Article
- Association Between the Expression of T Helper Type 17 Cell-Related Cytokines and Valve Damage in Rheumatic Heart Disease.Molecular biotechnology · 2025Article
- Technical Challenges in Studying Infectious Disease-Associated Pulmonary Hypertension in Low- and Middle-Income Countries with Limited Resources.Infectious disease reports · 2025Review
- Comparative Efficacy and Safety of Echocardiography Versus Radiation Guidance in Percutaneous Balloon Mitral Valvuloplasty: A Retrospective Study.Reviews in cardiovascular medicine · 2025Article
- A systematic methodology to capture the global pattern of rheumatic heart disease: the Rheumatic Heart Disease Endemicity Index (RHDEI).BMC global and public health · 2025Article
- Rheumatic Heart Disease Education Tools Integrated Into a Screening Program in Brazil: Acceptability and Knowledge Gain.Global heart · 2025Article
- A systematic review of machine learning in heart disease prediction.Turkish journal of biology = Turk biyoloji dergisi · 2025Review
- Research on rheumatic heart disease from 2013 to early 2024: a bibliometric analysis.Journal of cardiothoracic surgery · 2024Article
- Global Disparities in Outcomes of Pregnant Individuals With Rheumatic Heart Disease: A Scoping Review.JACC. Advances · 2024Article
- Article
- Application of Transthoracic Echocardiography for Cardiac Safety Evaluation in the Clinical Development Process of Vaccines Against Streptococcus pyogenes.Drugs in R&D · 2024Review
- Agreement between Handheld and Standard Echocardiography for Diagnosis of Latent Rheumatic Heart Disease in Brazilian Schoolchildren from High-Prevalence Settings (Agreement between Screening and Standard Echo for RHD).Diagnostics (Basel, Switzerland) · 2024Article
- Echocardiographic Screening of Rheumatic Heart Disease: Current Concepts and Challenges.Turkish archives of pediatrics · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 3 institutions in 3 countries.
Funding
Abstract
purpose of reviewRheumatic heart disease (RHD) is a neglected disease of poverty, which presents challenges for patients, communities, and health systems. These effects are magnified in low resource countries, which bear the highest disease burden. When considering the impact of RHD, it is imperative that we widen our lens in order to better understand how RHD impacts the over 40 million people currently living with this preventable condition and their communities. We aimed to perform an updated literature review on the global impact of RHD, examining a broad range of aspects from disease burden to impact on healthcare system to socioeconomic implications. RECENT
findingsRHD accounts for 1.6% of all cardiovascular deaths, resulting in 306,000 deaths yearly, with a much higher contribution in low- and middle-income countries, where 82% of the deaths occurred in 2015. RHD can result in severe health adverse outcomes, markedly heart failure, arrhythmias, stroke and embolisms, and ultimately premature death. Thus, preventive, diagnostic and therapeutic interventions are required, although insufficiently available in undersourced settings. As examples, anticoagulation management is poor in endemic regions - and novel oral anticoagulants cannot be recommended - and less than 15% of those in need have access to interventional procedures and valve replacement in Africa. RHD global impact remains high and unequally distributed, with a marked impact on lower resourced populations. This preventable disease negatively affects not only patients, but also the societies and health systems within which they live, presenting broad challenges and high costs along the pathway of prevention, diagnosis, and management.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.