Evidence map›Paper›PMID 34599373›Full record

ReviewMedizinische Klinik, Intensivmedizin und Notfallmedizin2021

[Crystalloids and colloids: fluid homeostasis and toxicity].

Michael Oppert

Abstract readReview
PubMed Publisher
In one paragraph

Review in Medizinische Klinik, Intensivmedizin und Notfallmedizin, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Michael OppertKlinik für Notfall- und Intensivmedizin, Klinikum Ernst von Bergmann gGmbH, Charlottenstraße 72, 14467, Potsdam, Deutschland. michael.oppert@klinikumevb.de.
Klinikum Ernst von Bergmann · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fluid balance is crucial in critically ill patients because mechanisms to counteract fluid dysbalances are limited. Therefore, an extremely important task of ICU staff is to assess and maintain fluid status. Fluid overload has been shown to have deleterious consequences for patients. Infusion fluids may be divided into colloid and crystalloid solutions. Within the crystalloids, balanced solutions have been shown to be superior over 0.9% saline with respect to acidosis, acute kidney injury, and mortality. The most widespread used colloid is hydroyethyl starch (HES). Compared to crystalloids, HES has a much greater volume effect. Despite this advantage, precautions must be undertaken with the use of HES. Side effects such as anaphylactic reactions and acute kidney injury are not uncommon; thus, critically ill patients and those at risk of kidney dysfunction should only receive HES preparations after careful consideration.

Indexed as

Plasma SubstitutesRehydration SolutionsColloidsCritical IllnessCrystalloid SolutionsFluid TherapyHomeostasisHumansHydroxyethyl Starch DerivativesIsotonic SolutionsResuscitationColloidsCrystalloid SolutionsHydroxyethyl Starch DerivativesIsotonic SolutionsPlasma SubstitutesRehydration SolutionsCrystalloid infusionsElectrolytesFluid balanceHydroxyethylated starchesParenteral infusionsSaline solution

Identifiers

PMID34599373
OpenAlexW3203952253

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.