Evidence map›Paper›PMID 34599357›Full record

ArticleParasitology research2021

Neospora caninum is not an important contributor to poor reproductive performance of primiparous ewes from southern Australia: evidence from a cross-sectional study.

Thomas Clune, Amy Lockwood, Serina Hancock, Mieghan Bruce, Andrew N Thompson, Sue Beetson, Angus J Campbell, Elsa Glanville, Daniel Brookes, Colin Trengove and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in Parasitology research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. Ovine Neosporosis: The Current Global Situation.Animals : an open access journal from MDPI · 2022
    Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Thomas CluneCentre for Animal Production and Health, Food Futures Institute, Murdoch University, 90 South Street, Murdoch, Western Australia, 6150, Australia.
Amy LockwoodCentre for Animal Production and Health, Food Futures Institute, Murdoch University, 90 South Street, Murdoch, Western Australia, 6150, Australia.
Serina HancockCentre for Animal Production and Health, Food Futures Institute, Murdoch University, 90 South Street, Murdoch, Western Australia, 6150, Australia.
Mieghan BruceCentre for Animal Production and Health, Food Futures Institute, Murdoch University, 90 South Street, Murdoch, Western Australia, 6150, Australia.
Andrew N ThompsonCentre for Animal Production and Health, Food Futures Institute, Murdoch University, 90 South Street, Murdoch, Western Australia, 6150, Australia.
Sue BeetsonCentre for Animal Production and Health, Food Futures Institute, Murdoch University, 90 South Street, Murdoch, Western Australia, 6150, Australia.
Angus J CampbellNossal Institute for Global Health, Melbourne School of Population and Global Health, University of Melbourne, Victoria, 3010, Australia.
Elsa GlanvilleMackinnon Project, Faculty of Veterinary & Agricultural Sciences, University of Melbourne, Werribee, Victoria, 3030, Australia.
Daniel BrookesMackinnon Project, Faculty of Veterinary & Agricultural Sciences, University of Melbourne, Werribee, Victoria, 3030, Australia.
Colin TrengoveSchool of Animal and Veterinary Science, University of Adelaide, Roseworthy, South Australia, 5371, Australia.
Ryan O'HandleySchool of Animal and Veterinary Science, University of Adelaide, Roseworthy, South Australia, 5371, Australia.
Caroline JacobsonCentre for Animal Production and Health, Food Futures Institute, Murdoch University, 90 South Street, Murdoch, Western Australia, 6150, Australia. C.Jacobson@murdoch.edu.au.ORCID http://orcid.org/0000-0001-9427-1941
Murdoch University · AUThe University of Melbourne · AUThe University of Adelaide · AU

Funding

meat and livestock australia B.AHE.0318
6 · The paper itself

Abstract

Neospora caninum has been implicated as a sporadic cause of abortion and perinatal deaths in sheep flocks globally. However, its significance as a reproductive pathogen for sheep in Australia remains unknown. The aims of this study were to (i) determine the seroprevalence of N. caninum in Australian breeding ewes and (ii) examine if natural exposure to N. caninum is associated with poor reproductive performance of primiparous ewes in southern Australia. Thirty flocks of primiparous ewes (aged 1-2 years old at lambing) from 28 farms in three states (Western Australia, South Australia and Victoria) were monitored between mating and lamb marking. Blood samples were also collected from multiparous mature ewes (aged 3 years or older) at each farm. Seroprevalence for anti-N. caninum IgG using indirect ELISA was determined for a subset of primiparous ewes that were predominantly determined to be pregnant and subsequently failed to rear a lamb (n = 1279) and randomly selected mature multiparous ewes with unknown reproductive status (n = 558). Neopsora caninum apparent seroprevalence was 0.16% (95% confidence interval 0.03%, 0.5%) in primiparous ewes, with seropositivity identified in two ewes from farms located in South Australia and Victoria. There was no evidence of seropositivity in mature ewes with apparent seroprevalence 0% (0%, 0.45%). These findings suggest that N. caninum infection was not widespread in primiparous ewes or mature multiparous ewes on these farms, and exposure to N. caninum infection was unlikely to explain abortion and perinatal mortalities observed for primiparous ewes.

Indexed as

CoccidiosisNeosporaAnimalsAntibodies, ProtozoanAustraliaCross-Sectional StudiesFemalePregnancySeroepidemiologic StudiesSheepSouth AustraliaAntibodies, ProtozoanInfectious abortionLamb mortalityLamb survivalMaiden eweNeospora caninumReproduction

Identifiers

PMID34599357
OpenAlexW3204793555

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.