Evidence map›Paper›PMID 34599281›Full record

ReviewModern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc2022

Integrating digital pathology into clinical practice.

Matthew G Hanna, Orly Ardon, Victor E Reuter, Sahussapont Joseph Sirintrapun, Christine England, David S Klimstra, Meera R Hameed

Erratum issuedAbstract readReview
PubMed Publisher
In one paragraph

Review in Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 75 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Observational
  17. Article
  18. Article
  19. Article
  20. Article

15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Matthew G HannaDepartment of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA. hannam@mskcc.org.ORCID http://orcid.org/0000-0002-7536-1746
Orly ArdonDepartment of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID http://orcid.org/0000-0001-8147-933X
Victor E ReuterDepartment of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Sahussapont Joseph SirintrapunDepartment of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Christine EnglandDepartment of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
David S KlimstraDepartment of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Meera R HameedDepartment of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA. hameedm@mskcc.org.ORCID http://orcid.org/0000-0002-2766-243X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The field of anatomic pathology has been evolving in the last few decades and the advancements have been largely fostered by innovative technology. Immunohistochemistry enabled a paradigm shift in discovery and diagnostic evaluation, followed by booming genomic advancements which allowed for submicroscopic pathologic characterization, and now the field of digital pathology coupled with machine learning and big data acquisition is paving the way to revolutionize the pathology medical domain. Whole slide imaging (WSI) is a disruptive technology where glass slides are digitized to produce on-screen whole slide images. Specifically, in the past decade, there have been significant advances in digital pathology systems that have allowed this technology to promote integration into clinical practice. Whole slide images (WSI), or digital slides, can be viewed and navigated comparable to glass slides on a microscope, as digital files. Whole slide imaging has increased in adoption among pathologists, pathology departments, and scientists for clinical, educational, and research initiatives. Integration of digital pathology systems requires a coordinated effort with numerous stakeholders, not only within the pathology department, but across the entire enterprise. Each pathology department has distinct needs, use cases and blueprints, however the framework components and variables for successful clinical integration can be generalized across any organization seeking to undergo a digital transformation at any scale. This article will review those components and considerations for integrating digital pathology systems into clinical practice.

Indexed as

MicroscopyPathology, ClinicalHumansPathologists

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.