ArticleMolecular psychiatry2021
Pathfinder: a gamified measure to integrate general cognitive ability into the biological, medical, and behavioural sciences.
Article in Molecular psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- The neurodevelopmental spectrum: phenotypic architecture, etiology, predictive utility, and specificity across development.Molecular psychiatry · 2026Article
- Gamification and Cognitive Factors: Research Hotspots, Knowledge Structure, and Future Directions Based on Bibliometric Analysis.Journal of Intelligence · 2026Article
- Sleep EEG foundation models reveal within-stage microstructure that improves health screening beyond traditional stages.Research square · 2026Article
- Disorder-Specific Genetic Effects Drive the Associations Between Psychopathology and Cognitive Functioning.Biological psychiatry global open science · 2026Article
- Charting the cognitive development of children using adult 'polygenic g scores'.bioRxiv : the preprint server for biology · 2025Article
- A genetic common factor underlying self-reported math ability and highest math class taken.Molecular psychiatry · 2025Article
- Examining the association between cognitive ability and emotional problems across childhood using a genetically informative design: could there be a causal relationship?Journal of child psychology and psychiatry, and allied disciplines · 2025Article
- The Genetic Specificity of Cognitive Tests After Controlling for General Cognitive Ability.Behavior genetics · 2025Article
- Multi-polygenic score prediction of mathematics, reading, and language abilities independent of general cognitive ability.Molecular psychiatry · 2025Article
- The Relationship Between Game-Related Assessment and Traditional Measures of Cognitive Ability-A Meta-Analysis.Journal of Intelligence · 2024Article
- Genetic associations between non-cognitive skills and academic achievement over development.Nature human behaviour · 2024Article
- Lingo: an automated, web-based deep phenotyping platform for language ability.medRxiv : the preprint server for health sciences · 2024Article
- Associations between executive functions assessed in different contexts in a genetically informative sample.Journal of experimental psychology. General · 2024Article
- Checking Different Video Game Mechanics to Assess Cognitive Abilities in Groups with and without Emotional Problems.Journal of Intelligence · 2023Article
- Genetic contributions of noncognitive skills to academic development.bioRxiv : the preprint server for biology · 2023Article
- Conventional twin studies overestimate the environmental differences between families relevant to educational attainment.NPJ science of learning · 2023Article
- Genetic contributions of noncognitive skills to academic development.Research square · 2023Article
- Enhancing online speech and language assessment: Item development for the remote adult language experiment (ReAL-E) tool.Journal of communication disordersArticle
- The genetics of specific cognitive abilities.IntelligenceArticle
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15 authors.
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Abstract
Genome-wide association (GWA) studies have uncovered DNA variants associated with individual differences in general cognitive ability (g), but these are far from capturing heritability estimates obtained from twin studies. A major barrier to finding more of this 'missing heritability' is assessment--the use of diverse measures across GWA studies as well as time and the cost of assessment. In a series of four studies, we created a 15-min (40-item), online, gamified measure of g that is highly reliable (alpha = 0.78; two-week test-retest reliability = 0.88), psychometrically valid and scalable; we called this new measure Pathfinder. In a fifth study, we administered this measure to 4,751 young adults from the Twins Early Development Study. This novel g measure, which also yields reliable verbal and nonverbal scores, correlated substantially with standard measures of g collected at previous ages (r ranging from 0.42 at age 7 to 0.57 at age 16). Pathfinder showed substantial twin heritability (0.57, 95% CIs = 0.43, 0.68) and SNP heritability (0.37, 95% CIs = 0.04, 0.70). A polygenic score computed from GWA studies of five cognitive and educational traits accounted for 12% of the variation in g, the strongest DNA-based prediction of g to date. Widespread use of this engaging new measure will advance research not only in genomics but throughout the biological, medical, and behavioural sciences.
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