ArticleScientific reports2021
Label-free fiber-optic spherical tip biosensor to enable picomolar-level detection of CD44 protein.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 20 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed, 53 citations in OpenAlex.
- Surface-Modified Extrinsic Semi-Distributed Interferometers for Fiber-Optic Refractive Index Detection and Biosensing.Biosensors · 2026Article
- Article
- Functionalization Techniques Empowering Optical Fiber Biosensors in Label-Free Cancer Biomarker Detection.Biosensors · 2025Review
- Digging into the Solubility Factor in Cancer Diagnosis: A Case of Soluble CD44 Protein.Biosensors · 2025Review
- Impact of Nanomedicine in Women's Metastatic Breast Cancer.Small (Weinheim an der Bergstrasse, Germany) · 2024Review
- Citrate polymer optical fiber for measuring refractive index based on LSPR sensor.Scientific reports · 2024Article
- Dynamic Measurement of a Cancer Biomarker: Towards In Situ Application of a Fiber-Optic Ball Resonator Biosensor in CD44 Protein Detection.Sensors (Basel, Switzerland) · 2024Article
- Portable optical fiber biosensors integrated with smartphone: technologies, applications, and challenges [Invited].Biomedical optics express · 2024Review
- All-fiber label-free optical fiber biosensors: from modern technologies to current applications [Invited].Biomedical optics express · 2024Review
- Photonic Crystal Surface Mode Real-Time Imaging of RAD51 DNA Repair Protein Interaction with the ssDNA Substrate.Biosensors · 2024Article
- Unpacking the packaged optical fiber bio-sensors: understanding the obstacle for biomedical application.Frontiers in bioengineering and biotechnology · 2024Review
- Enhancement of Refractive Index Sensitivity Using Small Footprint S-Shaped Double-Spiral Resonators for Biosensing.Sensors (Basel, Switzerland) · 2023Article
- Design of a novel hybrid multimode interferometer operating with both TE and TM polarizations for sensing applications.Optical and quantum electronics · 2023Article
- Highly Sensitive Zinc Oxide Fiber-Optic Biosensor for the Detection of CD44 Protein.Biosensors · 2022Article
- Review
- Ultralow Limit Detection of Soluble HER2 Biomarker in Serum with a Fiber-Optic Ball-Tip Resonator Assisted by a Tilted FBG.ACS measurement science au · 2022Article
- Cost-Effective Fiber Optic Solutions for Biosensing.Biosensors · 2022Review
- Article
- Monitoring and modulation of the tumor microenvironment for enhanced cancer modeling.Experimental biology and medicine (Maywood, N.J.) · 2022Review
- Perspectives on Assembling Coronavirus Spikes on Fiber Optics to Reveal Broadly Recognizing Antibodies and Generate a Universal Coronavirus Detector.Frontiers in bioengineering and biotechnology · 2021Article
Corrections and comments
- Erratum issued
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Increased level of CD44 protein in serum is observed in several cancers and is associated with tumor burden and metastasis. Current clinically used detection methods of this protein are time-consuming and use labeled reagents for analysis. Therefore exploring new label-free and fast methods for its quantification including its detection in situ is of importance. This study reports the first optical fiber biosensor for CD44 protein detection, based on a spherical fiber optic tip device. The sensor is easily fabricated from an inexpensive material (single-mode fiber widely used in telecommunication) in a fast and robust manner through a CO
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.