SynthesisEvidence-based mental health2021
Comparative efficacy and acceptability of psychotherapies for post-traumatic stress disorder in children and adolescents: a systematic review and network meta-analysis.
Synthesis in Evidence-based mental health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 42 citations in OpenAlex.
- Investigating factors influencing utilization of trauma-focused cognitive behavioral therapy among unaccompanied young refugees: an exploratory analysis.Child and adolescent psychiatry and mental health · 2025Article
- Cognitive behavioural therapies with a trauma focus for children and adolescents: a commentary on a systematic review and meta-analysis.Journal of family & child health · 2025Article
- MDMA-assisted psychotherapy for PTSD in adolescents: rationale, potential, risks, and considerations.European child & adolescent psychiatry · 2024Review
- Clinical Efficacy of Psychotherapeutic Interventions for Post-Traumatic Stress Disorder in Children and Adolescents: A Systematic Review and Analysis.Children (Basel, Switzerland) · 2024Review
- Screening for symptoms of childhood traumatic stress in the primary care pediatric clinic.BMC pediatrics · 2024Article
- Promising Effect of the Children in Disaster: Evaluation and Recovery Intervention on Trauma Symptoms and Quality of Life for Children and Adolescents: A Controlled Study.Psychiatry investigation · 2024Article
- Cross-Sectional and Descriptive Study on the Challenges and Awareness of Hispanic Parents Regarding Their Adolescents' Mental Health during the COVID-19 Pandemic.Healthcare (Basel, Switzerland) · 2024Article
- Psychological interventions for children with emotional and behavioral difficulties aged 5-12 years: An evidence review.Global mental health (Cambridge, England) · 2024Review
- The effectiveness of web-based training for parents on post-traumatic stress disorder in children.Frontiers in psychology · 2024Article
- Through a Developmental Lens: Emerging Insights to Understand and Treat Pediatric PTSD.The American journal of psychiatry · 2023Review
- Effectiveness of a school-based, lay counselor-delivered cognitive behavioral therapy for Chinese children with posttraumatic stress symptoms: a randomized controlled trial.The Lancet regional health. Western Pacific · 2023Article
- Implementing Trauma Informed Care in Human Services: An Ecological Scoping Review.Behavioral sciences (Basel, Switzerland) · 2022Article
- Carpe diem.Evidence-based mental health · 2022Article
- Pharmacological and non-pharmacological interventions for adults with ADHD: protocol for a systematic review and network meta-analysis.BMJ open · 2022Article
- Implementing trauma-focused cognitive behavioral therapy in Philadelphia: A 10-year evaluation.Implementation research and practiceArticle
Corrections and comments
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Authors and funding
18 authors at 10 institutions in 8 countries.
Funding
Abstract
backgroundAvailable evidence on the comparative efficacy and acceptability of psychotherapies for post-traumatic stress disorder (PTSD) in children and adolescents remains uncertain.
objectiveWe aimed to compare and rank the different types and formats of psychotherapies for PTSD in children and adolescents.
methodsWe searched eight databases and other international registers up to 31 December 2020. The pairwise meta-analyses and frequentist network meta-analyses estimated pooled standardised mean differences (SMDs) and ORs with random-effects model. Efficacy at post-treatment and follow-up, acceptability, depressive and anxiety symptoms were measured.
findingsWe included 56 randomised controlled trials with 5327 patients comparing 14 different types of psychotherapies and 3 control conditions. For efficacy, cognitive processing therapy (CPT), behavioural therapy (BT), individual trauma-focused cognitive-behavioural therapy (TF-CBT), eye movement desensitisation and reprocessing, and group TF-CBT were significantly superior to all control conditions at post-treatment and follow-up (SMDs between -2.42 and -0.25). Moreover, CPT, BT and individual TF-CBT were more effective than supportive therapy (SMDs between -1.92 and -0.49). Results for depressive and anxiety symptoms were similar to the findings for the primary outcome. Most of the results were rated as 'moderate' to 'very low' in terms of confidence of evidence.
conclusionsCPT, BT and individual TF-CBT appear to be the best choices of psychotherapy for PTSD in young patients. Other types and different ways of delivering psychological treatment can be alternative options. Clinicians should consider the importance of each outcome and the patients' preferences in real clinical practice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.