Evidence map›Paper›PMID 34598295›Full record

ArticleEuropean journal of dentistry2022

Periodontitis and Helicobacter pylori Infection: Eradication and Periodontal Therapy Combination.

Athanasios Tsimpiris, Andreas Grigoriadis, Ioannis Tsolianos, Ioannis Moschos, Dimitrios G Goulis, Georgios Kouklakis

Open access · hybridAbstract read
In one paragraph

Article in European journal of dentistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 3 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 3 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Effect of nonsurgical periodontal therapy on the eradication of gastricJournal of advanced periodontology & implant dentistry · 2025
    Article
  5. Association ofMicroorganisms · 2025
    Review
  6. Article
  7. Review
  8. Polymicrobial interactions ofJournal of oral microbiology · 2025
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Athanasios TsimpirisDepartment of Medicine, Democritus University of Thrace, Alexandroupolis, Greece.
Andreas GrigoriadisDental Sector, 424 General Military Training Hospital, Thessaloniki, Greece.ORCID 0000-0002-5542-2230
Ioannis TsolianosDental School, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Ioannis MoschosDepartment of Nursing, International Hellenic University, Thessaloniki, Greece.
Dimitrios G GoulisUnit of Reproductive Endocrinology, First Department of Obstetrics and Gynecology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Georgios KouklakisA' Department of Pathology, Department of Medicine, Democritus University of Thrace, Alexandroupolis, Greece.
Aristotle University of Thessaloniki · GRDemocritus University of Thrace · GRInternational Hellenic University · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study was aimed to assess (1) the prevalence of salivary and gastric MATERIALS AND

methodsThirty-three adults with periodontitis treated by quadrant scaling and root planning (QSRP). The simplified plaque index (PI), bleeding on probing index (BOP), probing pocket depth (PPD), and clinical attachment level (CAL) were assessed pretreatment and 3 months of posttreatment. The patients were tested for oral and gastric HP. Gastric HP (+) patients received eradication therapy. A control group of 32 periodontically healthy volunteers was tested for oral and gastric HP. Saliva samples were evaluated by real-time polymerase chain reaction (rtPCR); gastric HP was detected by urea breath test (UBT). STATISTICAL ANALYSIS: Normality of variables assessed by the Kolmogorov-Smirnov test, while the differences of pre- and post-treatment were analyzed by paired samples

resultsNo saliva samples were positive for HP. Gastric HP was detected in six patients with periodontitis and seven controls (

conclusionPeriodontitis was not associated with gastric HP infection. Saliva was not a gastric HP supply reservoir. Gastric HP infection was associated with advanced stages and grades of periodontitis. Although all periodontal clinical markers improved after QSRP, BOP, PI, and CAL, they were further improved when combined with eradication treatment. Periodontal evaluation and treatment combined with HP eradication are recommended in patients with HP gastric infection.

Identifiers

PMID34598295
PMCPMC8890927
OpenAlexW3202655676

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.