ArticleOptics letters2021
Depth resolution in multifocus laser speckle contrast imaging.
Article in Optics letters, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Enhancement of vascular visualization in laser speckle contrast imaging based on image algorithms.Journal of biomedical optics · 2025Article
- Laser speckle contrast imaging of hepatic microcirculation.Biomedical optics express · 2025Article
- Design and validation of a convolutional neural network for fast, model-free blood flow imaging with multiple exposure speckle imaging.Biomedical optics express · 2023Article
- Synchronization in renal microcirculation unveiled with high-resolution blood flow imaging.eLife · 2022Article
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Authors and funding
5 authors.
Funding
Abstract
Laser speckle contrast imaging (LSCI) can be used to evaluate blood flow based on spatial or temporal speckle statistics, but its accuracy is undermined by out-of-focus image blur. In this Letter, we show how the fraction of dynamic versus static light scattering is dependent on focus, and describe a deconvolution strategy to correct for out-of-focus blur. With the aid of a z-splitter, which enables instantaneous multifocus imaging, we demonstrate depth-resolved LSCI that can robustly extract multi-plane structural and flow-speed information simultaneously. This method is applied to in vivo imaging of blood vessels in a mouse cortex and provides improved estimates of blood flow speed throughout a depth range of 300µ
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