Evidence map›Paper›PMID 34598105›Full record

ArticleSchizophrenia research2021

Emotional and stigma-related experiences relative to being told one is at risk for psychosis.

Kristen A Woodberry, Kate S Powers, Caitlin Bryant, Donna Downing, Mary B Verdi, Katherine M Elacqua, Audrey R L Reuman, Leda Kennedy, Daniel I Shapiro, Michelle L West and 10 more

Open access · greenAbstract read
In one paragraph

Article in Schizophrenia research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 26 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Synergistic pathways to psychosis: understanding developmental risk and resilience factors.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Review
  4. Predicting risk of psychosis in primary care: a qualitative study.The British journal of general practice : the journal of the Royal College of General Practitioners · 2026
    Article
  5. Article
  6. Article
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  8. Ethical challenges in contemporary psychiatry: an overview and an appraisal of possible strategies and research needs.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2024
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors at 10 institutions in 1 country.

Kristen A WoodberryCenter for Psychiatric Research, Maine Medical Center, United States of America; Department of Psychiatry, Tufts School of Medicine, United States of America; Department of Psychiatry, Beth Israel Deaconess Medical Center, United States of America; Department of Psychiatry, Harvard Medical School, United States of America. Electronic address: kwoodberry@mmc.org.
Kate S PowersCenter for Psychiatric Research, Maine Medical Center, United States of America.
Caitlin BryantDepartment of Psychiatry, Beth Israel Deaconess Medical Center, United States of America; Department of Psychology, University of Massachusetts Boston, United States of America.
Donna DowningCenter for Psychiatric Research, Maine Medical Center, United States of America.
Mary B VerdiCenter for Psychiatric Research, Maine Medical Center, United States of America.
Katherine M ElacquaCenter for Psychiatric Research, Maine Medical Center, United States of America.
Audrey R L ReumanBowdoin College, United States of America.
Leda KennedyDepartment of Psychiatry, Beth Israel Deaconess Medical Center, United States of America; New York Psychiatric Institute, Columbia University, United States of America.
Daniel I ShapiroDepartment of Psychiatry, Beth Israel Deaconess Medical Center, United States of America; Department of Psychiatry, Harvard Medical School, United States of America; Department of Psychiatry and Behavioral Sciences, University of California Davis, United States of America.
Michelle L WestDepartment of Psychiatry, Beth Israel Deaconess Medical Center, United States of America; Department of Psychiatry, Harvard Medical School, United States of America; Anschutz Medical Campus, University of Colorado, United States of America; Department of Psychiatry, University of Colorado School of Medicine, United States of America.
Debbie HuangMailman School of Public Health, Columbia University, United States of America.
Francesca M CrumpDepartment of Psychology, Rowan University, United States of America.
Margaux M GrivelSchool of Global Public Health, New York University, United States of America.
Drew BlascoSchool of Global Public Health, New York University, United States of America.
Shaynna N HerreraDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, United States of America.
Cheryl M CorcoranDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, United States of America; James J Peter Veterans Affairs Medical Center, United States of America.
Larry J SeidmanDepartment of Psychiatry, Beth Israel Deaconess Medical Center, United States of America; Department of Psychiatry, Harvard Medical School, United States of America.
Bruce G LinkDepartment of Sociology, University of California, Riverside, United States of America.
William R McFarlaneCenter for Psychiatric Research, Maine Medical Center, United States of America; Department of Psychiatry, Tufts School of Medicine, United States of America.
Lawrence H YangMailman School of Public Health, Columbia University, United States of America; School of Global Public Health, New York University, United States of America.
Maine Medical Center · USBeth Israel Deaconess Medical Center · USColumbia University · USNew York University · USBowdoin College · USHarvard University · USIcahn School of Medicine at Mount Sinai · USJames J. Peters VA Medical Center · USRowan University · USUniversity of California, Riverside · US

Funding

Thought disorder and social cognition in clinical risk states for schizophreniaR01MH107558 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI CORCORAN, CHERYL MARY · 2016 to 2020
$3.3M
Stigma Associated with a High-Risk State for PsychosisR01MH096027 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SUSSER, EZRA S., YANG, LAWRENCE H · 2012 to 2016
$2.6M
Innovative Intervention for Reducing Stress Reactivity and Risk for PsychosisK23MH102358 · NIMH · MAINEHEALTH · PI WOODBERRY, KRISTEN ANNE · 2014 to 2017
$722k
Developing Clinical Translational Tools to Communicate Genetic Risk to Individuals who are at Clinical High Risk for PsychosisR21HG010420 · NHGRI · NEW YORK UNIVERSITY · PI YANG, LAWRENCE H · 2019 to 2020
$470k
Exploring affect variability, symptoms, and social context in psychotic-spectrum youthR21MH116240 · NIMH · MAINEHEALTH · PI WOODBERRY, KRISTEN ANNE · 2018 to 2019
$400k
NHGRI NIH HHS R21 HG010420NIMH NIH HHS K23 MH102358NIMH NIH HHS R01 MH096027NIMH NIH HHS R01 MH107558NIMH NIH HHS R21 MH116240
6 · The paper itself

Abstract

objectiveDespite the appeal of early intervention in psychosis, there is concern that identifying youth as having high psychosis risk (PR) may trigger stigma. This study employed a pre-post design to measure change in PR participants' emotions about PR upon being told of their PR status and according to whether this was the first time receiving this information.

methodsParticipants (n = 54) identified as at PR via structured interview rated their emotions about PR before and after being told they were at PR. Qualitative analyses explored the valence of participant reflections on being given this information.

resultsParticipants reported significantly less negative emotion after being told of their PR status (p < .001), regardless of whether they were hearing this for the first time (p = .72). There was no change in positive emotions or the predominant belief that they should keep their PR status private. Most participants commented positively about the process of feedback but negatively about its impact on their self-perceptions and/or expectations of others' perceptions of them.

conclusionThis is the first study to collect pre-post data related to being told one is at PR and to examine quantitative and qualitative responses across and within individuals. For a majority of participants, clinical feedback stimulated negative stereotypes even as it relieved some distress. To actively address internalized stigma, clinicians providing feedback to PR youth must attend to the positive and negative impacts on how youth think about themselves as well as how they feel.

Indexed as

Psychotic DisordersSocial StigmaAdolescentEmotionsHumansSelf ConceptClinical high riskFeedbackLabelingPre-postProdrome

Identifiers

PMID34598105
PMCPMC8633064
OpenAlexW3204926121

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.