Evidence map›Paper›PMID 34598100›Full record

ArticleDrug and alcohol dependence2021

The impact of the national stay-at-home order on emergency department visits for suspected opioid overdose during the first wave of the COVID-19 pandemic.

Elisabeth D Root, Svetla Slavova, Marc LaRochelle, Daniel J Feaster, Jennifer Villani, Jolene Defiore-Hyrmer, Nabila El-Bassel, Rosa Ergas, Kitty Gelberg, Rebecca Jackson and 4 more

Open access · greenAbstract read
In one paragraph

Article in Drug and alcohol dependence, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 9 institutions in 1 country.

Elisabeth D RootDepartment of Geography and Division of Epidemiology, The Ohio State University, Columbus, OH, United States. Electronic address: eroot@idmod.org.
Svetla SlavovaDepartment of Biostatistics, University of Kentucky, Lexington, KY, United States.
Marc LaRochelleClinical Addiction Research and Education Unit, Section of General Internal Medicine, Department of Medicine, Boston University School of Medicine and Boston Medical Center, Boston, MA, United States.
Daniel J FeasterDepartment of Public Health Sciences, University of Miami Miller School of Medicine, Miami, FL, United States.
Jennifer VillaniNational Institutes of Health, National Institute on Drug Abuse, Bethesda, MD, United States.
Jolene Defiore-HyrmerBureau of Health Improvement and Wellness, Ohio Department of Health, Columbus, OH, United States.
Nabila El-BasselSchool of Social Work, Columbia University, New York, NY, United States.
Rosa ErgasMassachusetts Department of Public Health, Bureau of Infectious Disease and Laboratory Sciences, Jamaica Plain, MA, United States.
Kitty GelbergNew York State Department of Health, Office of Drug User Health, Albany, NY, United States.
Rebecca JacksonDepartments of Physical Medicine and Rehabilitation, Internal Medicine/ Endocrinology, and Diabetes and Metabolism, Ohio State University, Columbus, OH, United States.
Kara ManchesterOhio Violence and Injury Prevention Program, Ohio Department of Health, Columbus, OH, United States.
Megha ParikhMassachusetts Department of Public Health, Bureau of Infectious Disease and Laboratory Sciences, Jamaica Plain, MA, United States.
Peter RockCenter for Clinical and Translational Science, University of Kentucky, Lexington, KY, United States.
Sharon L WalshDepartment of Behavioral Science and Center on Drug and Alcohol Research, University of Kentucky College of Medicine, Lexington, KY, United States.
University of Kentucky · USMassachusetts Department of Public Health · USOhio Department of Health · USThe Ohio State University · USBoston University · USColumbia University · USNational Institutes of Health · USNew York State Department of Health · USUniversity of Miami · US

Funding

Kentucky CAN HEAL (Communities and Networks Helping End Addiction Long-term)UM1DA049406 · NIDA · UNIVERSITY OF KENTUCKY · PI WALSH, SHARON L. · 2019 to 2022
$81.7M
NIDA NIH HHS UM1 DA049406
6 · The paper itself

Abstract

backgroundAlthough national syndromic surveillance data reported declines in emergency department (ED) visits after the declaration of the national stay-at-home order for COVID-19, little is known whether these declines were observed for suspected opioid overdose.

methodsThis interrupted time series study used syndromic surveillance data from four states participating in the HEALing Communities Study: Kentucky, Massachusetts, New York, and Ohio. All ED encounters for suspected opioid overdose (n = 48,301) occurring during the first 31 weeks of 2020 were included. We examined the impact of the national public health emergency for COVID-19 (declared on March 14, 2020) on trends in ED encounters for suspected opioid overdose.

resultsThree of four states (Massachusetts, New York and Ohio) experienced a statistically significant immediate decline in the rate of ED encounters for suspected opioid overdose (per 100,000) after the nationwide public health emergency declaration (MA: -0.99; 95 % CI: -1.75, -0.24; NY: -0.10; 95 % CI, -0.20, 0.0; OH: -0.33, 95 % CI: -0.58, -0.07). After this date, Ohio and Kentucky experienced a sustained rate of increase for a 13-week period. New York experienced a decrease in the rate of ED encounters for a 10-week period, after which the rate began to increase. In Massachusetts after a significant immediate decline in the rate of ED encounters, there was no significant difference in the rate of change for a 6-week period, followed by an immediate increase in the ED rate to higher than pre-COVID levels.

conclusionsThe heterogeneity in the trends in ED encounters between the four sites show that the national stay-at-home order had a differential impact on opioid overdose ED presentation in each state.

Indexed as

COVID-19Drug OverdoseOpiate OverdoseAnalgesics, OpioidEmergency Service, HospitalHumansPandemicsSARS-CoV-2Analgesics, OpioidCOVID-19Emergency department encounterHEALing Communities StudyOpioid use disorderSegmented regressionSyndromic surveillance

Identifiers

PMID34598100
PMCPMC8397502
OpenAlexW3197684626

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.