Evidence map›Paper›PMID 34597856›Full record

ArticleBrain stimulation

Concurrent conventional & high-definition transcranial direct current stimulation for treatment of schizophrenia with co-morbid obsessive-compulsive disorder: A case report.

Swarna Buddha Nayok, Harsh Pathak, Satish Suhas, Vani H Thimmashetty, Prakrithi Shivaprakash, Ragibommanahalli M Madhu Sudhan, Vanteemar S Sreeraj, Janardhanan C Narayanaswamy, Ganesan Venkatasubramanian

Open access · goldAbstract readCase ReportsLetter
In one paragraph

Article in Brain stimulation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 13 citations in OpenAlex.

  1. Churning Better Transcranial Direct Current Stimulation Outcome with Accelerated Protocols: Understanding the Non-linear Dynamics through Metaplasticity.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2025
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Swarna Buddha NayokDepartment of Clinical Neurosciences, National Institute of Mental Health and NeuroSciences (NIMHANS), Bengaluru 560029, Karnataka, India; Department of Psychiatry, National Institute of Mental Health and NeuroSciences (NIMHANS), Bengaluru 560029, Karnataka, India; WISER Neuromodulation Program, Department of Psychiatry, National Institute of Mental Health and NeuroSciences (NIMHANS), Bengaluru 560029, Karnataka, India.
Harsh PathakDepartment of Psychiatry, National Institute of Mental Health and NeuroSciences (NIMHANS), Bengaluru 560029, Karnataka, India; WISER Neuromodulation Program, Department of Psychiatry, National Institute of Mental Health and NeuroSciences (NIMHANS), Bengaluru 560029, Karnataka, India.
Satish SuhasDepartment of Psychiatry, National Institute of Mental Health and NeuroSciences (NIMHANS), Bengaluru 560029, Karnataka, India; WISER Neuromodulation Program, Department of Psychiatry, National Institute of Mental Health and NeuroSciences (NIMHANS), Bengaluru 560029, Karnataka, India.
Vani H ThimmashettyWISER Neuromodulation Program, Department of Psychiatry, National Institute of Mental Health and NeuroSciences (NIMHANS), Bengaluru 560029, Karnataka, India.
Prakrithi ShivaprakashDepartment of Psychiatry, National Institute of Mental Health and NeuroSciences (NIMHANS), Bengaluru 560029, Karnataka, India.
Ragibommanahalli M Madhu SudhanDepartment of Psychiatry, National Institute of Mental Health and NeuroSciences (NIMHANS), Bengaluru 560029, Karnataka, India.
Vanteemar S SreerajDepartment of Psychiatry, National Institute of Mental Health and NeuroSciences (NIMHANS), Bengaluru 560029, Karnataka, India; WISER Neuromodulation Program, Department of Psychiatry, National Institute of Mental Health and NeuroSciences (NIMHANS), Bengaluru 560029, Karnataka, India. Electronic address: vs8sreeraj@yahoo.com.
Janardhanan C NarayanaswamyDepartment of Psychiatry, National Institute of Mental Health and NeuroSciences (NIMHANS), Bengaluru 560029, Karnataka, India; WISER Neuromodulation Program, Department of Psychiatry, National Institute of Mental Health and NeuroSciences (NIMHANS), Bengaluru 560029, Karnataka, India.
Ganesan VenkatasubramanianDepartment of Clinical Neurosciences, National Institute of Mental Health and NeuroSciences (NIMHANS), Bengaluru 560029, Karnataka, India; Department of Psychiatry, National Institute of Mental Health and NeuroSciences (NIMHANS), Bengaluru 560029, Karnataka, India; WISER Neuromodulation Program, Department of Psychiatry, National Institute of Mental Health and NeuroSciences (NIMHANS), Bengaluru 560029, Karnataka, India.
National Institute of Mental Health and Neurosciences · IN

Funding

DBT-Wellcome Trust India Alliance IA/CRC/19/1/610005Wellcome Trust
6 · The paper itself

Abstract

Non-invasive brain stimulation techniques such as conventional transcranial direct current stimulation (tDCS) and high definition tDCS (HD-tDCS) are increasingly being used as add-on treatment options in schizophrenia and obsessive-compulsive disorder (OCD). This is reporting of the use of a novel accelerated, symptom-specific, add-on tDCS (combining conventional and high definition) protocol in a patient with both schizophrenia and OCD. The intervention showed clinical utility by reducing both schizophrenia and OCD symptoms.

Indexed as

Obsessive-Compulsive DisorderSchizophreniaTranscranial Direct Current StimulationComorbidityHumansTreatment OutcomeAccelerated tDCSHigh-definition transcranial direct current stimulation (HD-tDCS)Obsessive-compulsive disorder (OCD)SchizophreniaTranscranial direct current stimulation (tDCS)

Identifiers

PMID34597856
PMCPMC7614562
OpenAlexW3202863298

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.