Evidence map›Paper›PMID 34597475›Full record

ArticlePediatric pulmonology2021

Agreement of parent- and child-reported wheeze and its association with measurable asthma traits.

Rebeca Mozun, Cristina Ardura-Garcia, Eva S L Pedersen, Myrofora Goutaki, Jakob Usemann, Florian Singer, Philipp Latzin, Alexander Moeller, Claudia E Kuehni, LUIS study group

Abstract read
In one paragraph

Article in Pediatric pulmonology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Exercise-induced symptoms in young childhood cancer survivors.Journal of cancer survivorship : research and practice · 2025
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rebeca MozunInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.ORCID 0000-0002-5237-8668
Cristina Ardura-GarciaInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.ORCID 0000-0001-7924-518X
Eva S L PedersenInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.ORCID 0000-0003-0293-9954
Myrofora GoutakiInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.ORCID 0000-0001-8036-2092
Jakob UsemannDepartment of Respiratory Medicine, University Children's Hospital Zurich and Childhood Research center, University of Zurich, Zurich, Switzerland.ORCID 0000-0002-9987-2866
Florian SingerDivision of Paediatric Respiratory Medicine and Allergology, Department of Paediatrics, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.ORCID 0000-0003-3471-5664
Philipp LatzinDivision of Paediatric Respiratory Medicine and Allergology, Department of Paediatrics, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.ORCID 0000-0002-5239-1571
Alexander MoellerDepartment of Respiratory Medicine, University Children's Hospital Zurich and Childhood Research center, University of Zurich, Zurich, Switzerland.ORCID 0000-0001-7284-4251
Claudia E KuehniInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.ORCID 0000-0001-8957-2002
LUIS study group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesIn epidemiological studies, childhood asthma is usually assessed with questionnaires directed at parents or children, and these may give different answers. We studied how well parents and children agreed when asked to report symptoms of wheeze and investigated whose answers were closer to measurable traits of asthma.

methodsLuftiBus in the school is a cross-sectional survey of respiratory health among Swiss schoolchildren aged 6-17 years. We applied questionnaires to parents and children asking about wheeze and exertional wheeze in the past year. We assessed agreement between parent-child answers with Cohen's kappa (k), and associations of answers from children and parents with fractional exhaled nitric oxide (FeNO) and forced expiratory volume in 1 s over forced vital capacity (FEV

resultsWe received questionnaires from 3079 children and their parents. Agreement was poor for reported wheeze (k = 0.37) and exertional wheeze (k = 0.36). Median FeNO varied when wheeze was reported by children (19 ppb, interquartile range [IQR]: 9-44), parents (22 ppb, IQR: 12-46), both (31 ppb, IQR: 16-55), or neither (11 ppb, IQR: 7-19). Median absolute FEV

conclusionOur findings suggest that surveying both parents and children and combining their responses can help us to better identify children with measurable asthma traits.

Indexed as

AsthmaFractional Exhaled Nitric Oxide TestingBreath TestsChildCross-Sectional StudiesForced Expiratory VolumeHumansNitric OxideParentsNitric Oxideagreementchildfractional exhaled nitric oxideparentspirometry

Identifiers

PMID34597475
PMCPMC9293286

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.