Evidence map›Paper›PMID 34597457›Full record

ArticleChemphyschem : a European journal of chemical physics and physical chemistry2021

Ionization of 2- and 4(5)-Nitroimidazoles Radiosensitizers: A "Kinetic Competition" Between NO

Mauro Satta, Anna Rita Casavola, Antonella Cartoni, Mattea Carmen Castrovilli, Daniele Catone, Jacopo Chiarinelli, Stefano Borocci, Lorenzo Avaldi, Paola Bolognesi

Abstract read
In one paragraph

Article in Chemphyschem : a European journal of chemical physics and physical chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Halogen Migration in the Photofragmentation of Halothane.Molecules (Basel, Switzerland) · 2025
    Article
  2. Ionic Route to Atmospheric Relevant HOMolecules (Basel, Switzerland) · 2024
    Article
  3. Ionization of 2- and 4(5)-Nitroimidazoles Radiosensitizers: A "Kinetic Competition" Between NOChemphyschem : a European journal of chemical physics and physical chemistry · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mauro SattaIstituto per lo Studio dei Materiali Nanostrutturati (ISMN-CNR), Dipartimento di Chimica, Università degli studi di Roma La Sapienza, P.le Aldo Moro 5, 00185, Roma, Italy.ORCID 0000-0001-5795-4700
Anna Rita CasavolaIstituto di Struttura della Materia (ISM-CNR), Area della Ricerca di Roma 1, Via Salaria Km 29,300, 00016, Monterotondo Scalo (RM), Italy.ORCID 0000-0001-9805-2842
Antonella CartoniDipartimento di Chimica, Università degli studi di Roma La Sapienza, Pl.e Aldo Moro 5, 00185, Roma, Italy.ORCID 0000-0001-8170-1121
Mattea Carmen CastrovilliIstituto di Struttura della Materia (ISM-CNR), Area della Ricerca di Roma 1, Via Salaria Km 29,300, 00016, Monterotondo Scalo (RM), Italy.ORCID 0000-0002-7909-5115
Daniele CatoneIstituto di Struttura della Materia (ISM-CNR), Area della Ricerca di Roma 2, Via del Fosso del Cavaliere 10, 00133, Roma, Italy.ORCID 0000-0002-7649-2756
Jacopo ChiarinelliIstituto di Struttura della Materia (ISM-CNR), Area della Ricerca di Roma 1, Via Salaria Km 29,300, 00016, Monterotondo Scalo (RM), Italy.
Stefano BorocciDipartimento per l'Innovazione nei Sistemi Biologici, Agroalimentari e Forestali (DIBAF), Università della Tuscia, Viterbo, Italy.ORCID 0000-0003-4931-3019
Lorenzo AvaldiIstituto di Struttura della Materia (ISM-CNR), Area della Ricerca di Roma 1, Via Salaria Km 29,300, 00016, Monterotondo Scalo (RM), Italy.ORCID 0000-0002-2990-7330
Paola BolognesiIstituto di Struttura della Materia (ISM-CNR), Area della Ricerca di Roma 1, Via Salaria Km 29,300, 00016, Monterotondo Scalo (RM), Italy.ORCID 0000-0002-6543-6628

Funding

COST
6 · The paper itself

Abstract

Nitroimidazoles are a class of chemicals with a remarkable broad spectrum of applications from the production of explosives to the use as radiosensitizers in radiotherapy. The understanding of thedynamics of their fragmentation induced by ionizing sources is of fundamental interest. The goal of this work is to theoretically investigate the kinetic competition between the two most important decomposition channels of 2, 4 and 5-Nitroimidazole cations: the NO and NO

Indexed as

density functional calculationshigh-energy density materialsradiotherapyrate coefficientvariational transition state theory

Identifiers

PMID34597457
PMCPMC9293481

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.