Evidence map›Paper›PMID 34597322›Full record

ArticlePloS one2021

Hyperendemicity of cysticercosis in Madagascar: Novel insights from school children population-based antigen prevalence study.

Jean-François Carod, Frédéric Mauny, Anne Laure Parmentier, Maxime Desmarets, Mahenintsoa Rakotondrazaka, Alice Brembilla, Véronique Dermauw, Julien Razafimahefa, Rondro Mamitiana Ramahefarisoa, Marcellin Andriantseheno and 3 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 4 countries.

Jean-François CarodLaboratoire de Parasitologie, Pasteur Institute of Madagascar, Antananarivo, Madagascar.ORCID 0000-0002-7472-7160
Frédéric MaunyUnité de méthodologie en recherche clinique, épidémiologie et santé publique, CIC Inserm 143, University Hospital Center, Besançon, France.
Anne Laure ParmentierUnité de méthodologie en recherche clinique, épidémiologie et santé publique, CIC Inserm 143, University Hospital Center, Besançon, France.
Maxime DesmaretsUnité de méthodologie en recherche clinique, épidémiologie et santé publique, CIC Inserm 143, University Hospital Center, Besançon, France.ORCID 0000-0002-3801-5297
Mahenintsoa RakotondrazakaLaboratoire de Parasitologie, Pasteur Institute of Madagascar, Antananarivo, Madagascar.
Alice BrembillaLaboratoire Chrono environnement, UMR 6249, CNRS-université de Franche Comté, Université de Bourgogne Franche-Comté, Besançon, France.
Véronique DermauwDepartment of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
Julien RazafimahefaNeurology Unit, Hospital Befelatanana, Antananarivo, Madagascar.ORCID 0000-0001-6540-2746
Rondro Mamitiana RamahefarisoaLaboratoire de Parasitologie, Pasteur Institute of Madagascar, Antananarivo, Madagascar.
Marcellin AndriantsehenoNeurology Unit, Hospital Befelatanana, Antananarivo, Madagascar.
Sarah BaillyEpidemiology Unit, Pasteur Institute of French Guiana, Cayenne, French Guiana.
Didier MénardMalaria Research Unit, Pasteur Institute of Madagascar, Antananarivo, Madagascar.ORCID 0000-0003-1357-4495
Pierre DornyDepartment of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.ORCID 0000-0001-5381-7987
Institut Pasteur de Madagascar · MGCentre National de la Recherche Scientifique · FRInstituut voor Tropische Geneeskunde · BEUniversity of Antananarivo · MGInserm · FRUniversity of French Guiana · GF

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTaenia solium (Ts) cysticercosis is a neglected zoonotic disease particularly prevalent in Madagascar. Few data are available for children, current data mainly rely on antibody prevalence. We sought to determine the Ts-antigen seroprevalence-determining active cysticercosis-amongst school children from various cities in Madagascar (excluding the capital) and evaluated associated risk factors.

methodsIn seven cities in Madagascar, the presence of cysticercosis in school children (n = 1751) was investigated in 2007 using the B158/B60 antigen (Ag)-ELISA.

resultsThe overall prevalence based on Ag detection was 27.7% [95%CI: 10-37%]. Risk factors associated with Ag positivity were age, biotope, altitude and annual average rainfall.

conclusionThese results highlight the high prevalence of active cysticercosis in Madagascar among school children in an urban setting. This high prevalence as well as the risk factors unraveled point to the emergency to implement appropriate Public Health measure son a national scale.

Indexed as

AdolescentAnimalsAntibodies, HelminthChildChild, PreschoolCitiesCross-Sectional StudiesCysticercosisFemaleHumansMadagascarMalePrevalenceRisk FactorsSchoolsSeroepidemiologic StudiesAntibodies, Helminth

Identifiers

PMID34597322
PMCPMC8486106
OpenAlexW3204958265

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.