Evidence map›Paper›PMID 34597318›Full record

Trial reportPloS one2021

Effects of low-level laser therapy versus soft occlusive splints on mouth opening and surface electromyography in females with temporomandibular dysfunction: A randomized-controlled study.

Tamer Shousha, Mohamed Alayat, Ibrahim Moustafa

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06762912 (The Short-term Effect of Low-load Resistance Training with Blood-flow Restriction on Somatosensory-evoked Potentials in Healthy Young Adults - a Randomized Crossover Trial), which is not on this map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06762912 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

The Short-term Effect of Low-load Resistance Training with Blood-flow Restriction on Somatosensory-evoked Potentials in Healthy Young Adults - a Randomized Crossover Trial

TypeinterventionalSponsorUniversity of SharjahRan2025 to 2025Enrolled30ConditionsThe Current Study Focuses on Investigating the Short-term Effect of BFRT on the Somatosensory System Among Healthy Young AdultsArmsPassive application of BFR cuff, Resistance exercise with BFR, Resistance exercise without BFR
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 34 citations in OpenAlex.

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  3. Occlusal interventions for managing temporomandibular disorders.The Cochrane database of systematic reviews · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 3 countries.

Tamer ShoushaDepartment of Physiotherapy, College of Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.ORCID 0000-0002-0712-4490
Mohamed AlayatFaculty of Physical Therapy, Cairo University, Cairo, Egypt.
Ibrahim MoustafaDepartment of Physiotherapy, College of Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.
Cairo University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLow level lasers have been used as an alternative pain relief therapy for muscle and joint pain, since it induces analgesic, anti-inflammatory, and biomodulation effects of the physiological cell functions. The effectiveness of low-level laser therapy in temporomandibular joint dysfunction (TMD) treatment, however, is not well established. Although Surface electromyography (sEMG) has been suggested as a complementary means in TMD diagnosis, the effect of conservative treatments on muscle activity has not yet been thoroughly correlated with (sEMG) findings. PURPOSE: To assess the efficacy of low-level laser therapy (LLLT) as compared to occlusive splint therapy (OST) on the TMJ opening index (TOI) and sEMG of masticatory muscles. MATERIALS AND

methods112 female subjects suffering from unilateral myogenous TMD, aged 21-30 years-old, were recruited and divided into three groups: LLLT; soft occlusive splint therapy OST and a waitlist group as controls. OUTCOME MEASURES: TMJ opening index (TOI), Visual analogue scale (VAS), surface electromyography (sEMG).

resultsA significant reduction was reported in TOI, VAS and the sEMG within the LLLT and OST groups as well as significant decrease in all outcomes between groups in favor of the LLLT group (P< 0.0001). Meanwhile, there was a weak significant difference within the control group probably attributed to the analgesic. Post-hoc pairwise comparisons between groups [control vs occlusive splints, control vs low-level laser and low-level laser vs occlusive splints] revealed significant differences in the VAS and TOI [P = 0.0001; 95% CI: 0.9-2.2, 1.61-4.01, 0.65-1.96].

conclusionsFindings support an evident short term therapeutic effect of the LLLT on improving VAS, TOI and sEMG in females suffering from myogenous TMD.

Indexed as

AdultElectromyographyFacial PainFemaleHumansLow-Level Light TherapyTemporomandibular Joint DisordersTreatment OutcomeYoung Adult

Identifiers

PMID34597318
PMCPMC8486092
OpenAlexW3201751398

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.