ArticleRadiographics : a review publication of the Radiological Society of North America, Inc2021
Mucin-producing Cystic Hepatobiliary Neoplasms: Updated Nomenclature and Clinical, Pathologic, and Imaging Features.
Article in Radiographics : a review publication of the Radiological Society of North America, Inc, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 43 citations in OpenAlex.
- Mucinous cystic neoplasm of the liver with biliary prolapse mimicking intraductal papillary neoplasm of the bile duct: a case report.Abdominal radiology (New York) · 2026Article
- Article
- Undifferentiated embryonal sarcoma of the liver presenting as a complex mixed solid-cystic hepatic lesion in a young adult: A case report.Radiology case reports · 2026Article
- Mucin-producing cysts of the liver. Radiologic-pathologic correlation.Abdominal radiology (New York) · 2026Review
- Hepatic mucinous cystic neoplasm with hematoma: A case report.Radiology case reports · 2026Article
- Differentiating multilocular hepatic cysts from mucinous cystic neoplasms: characteristic imaging signs and a machine learning diagnostic framework.Quantitative imaging in medicine and surgery · 2026Article
- Successful Management of a 27-cm Mucinous Cystic Neoplasm of the Liver With Laparoscopic Excision: A Case Report.Cureus · 2026Article
- Article
- Mucinous cystic neoplasms of the liver: current insights into epidemiology, diagnosis, and treatment.Frontiers in surgery · 2026Review
- Intraductal papillary neoplasm of the biliary tract with typical clinicopathological, endoscopic features: A case report.World journal of gastrointestinal surgery · 2025Article
- Neoplastic premalignant pancreatobiliary lesions: current update on the spectrum of lesions and their imaging appearances.Abdominal radiology (New York) · 2025Review
- Refining imaging criteria for mucinous cystic neoplasm of the liver: simplified diagnostic approach.European radiology · 2025Article
- Cystic lesions and their mimics involving the intrahepatic bile ducts and peribiliary space: diagnosis, complications, and management.Abdominal radiology (New York) · 2025Review
- Classification of intrahepatic cholangiocarcinoma.Abdominal radiology (New York) · 2025Review
- Robotic left hepatectomy for the management of mucinous cystic neoplasm of the liver with atypical presentation inside the biliary tract: a case report.Journal of surgical case reports · 2025Article
- [Case of Intraductal Papillary Neoplasm of Bile Duct with Invasive Carcinoma after Choledochoduodenostomy for Intrahepatic Duct Stones].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2025Article
- To identify important MRI features to differentiate hepatic mucinous cystic neoplasms from septated hepatic cysts based on random forest.Japanese journal of radiology · 2024Article
- Imaging features and management of focal liver lesions.World journal of radiology · 2024Review
- Hepatic cysts: a survival guide.Radiologia brasileiraArticle
- Intraductal papillary neoplasms of the bile ducts-what can be seen with ultrasound?Endoscopic ultrasoundReview
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Authors and funding
7 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cystic hepatobiliary neoplasms with mucin-producing epithelium-mucinous cystic neoplasm of the liver (MCN) and intraductal papillary neoplasm of the bile duct (IPNB)-are rare and distinct entities that have unique clinical, pathologic, and imaging features. They are differentiated pathologically by the presence of subepithelial ovarian-like hypercellular stroma (OLS), which is the defining histopathologic feature of MCN. MCN is commonly a benign, large, solitary, symptomatic, multiloculated cystic mass without biliary communication that occurs in middle-aged women. On the other hand, IPNBs are a heterogeneous spectrum of tumors, which are commonly associated with invasive carcinoma, occur in older patients, and can be differentiated from MCN by communication with the biliary tree, intraductal masses, associated biliary ductal dilatation, and absent OLS. Understanding of these rare neoplasms has grown and evolved over time and continues to today, but uncertainty and controversy persist, related to the rarity of these tumors, relatively recent designation as separate entities, inherent clinicopathologic heterogeneity, overlapping imaging features, and the fact that many prior studies likely included MCN and cystic IPNB together as a single entity. Confusion regarding these neoplasms is evident by historical inconsistencies and nonstandardized nomenclature through the years. Awareness of these entities is important for the interpreting radiologist to suggest a particular diagnosis or generate a meaningful differential diagnosis in the appropriate setting, and is of particular significance as MCN and cystic IPNB have overlapping imaging features with other more common hepatobiliary cystic masses but have different management and prognosis.
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