Evidence map›Paper›PMID 34597229›Full record

ArticleRadiographics : a review publication of the Radiological Society of North America, Inc2021

Imaging Evaluation of Living Liver Donor Candidates: Techniques, Protocols, and Anatomy.

Amir A Borhani, Khaled M Elsayes, Roberta Catania, Avinash Kambadakone, Alessandro Furlan, Andrea S Kierans, Amita Kamath, Carla Harmath, Natally Horvat, Abhinav Humar and 1 more

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Radiographics : a review publication of the Radiological Society of North America, Inc, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07586046 (A Prospective Dose-Escalation Study to Define an Ablative Dose of Yttrium-90 Transarterial Radioembolization Using Advanced Dosimetry and Functional MRI), which is not on this map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07586046 phase2not yet recruitingnot on this mapstarted 2026, after this paper: background citation

A Prospective Dose-Escalation Study to Define an Ablative Dose of Yttrium-90 Transarterial Radioembolization Using Advanced Dosimetry and Functional MRI (MARGIN Study)

TypeinterventionalSponsorNorthwestern UniversityRan2026 to 2029Enrolled30ConditionsHCC - Hepatocellular CarcinomaArmsYttrium-90 Radiation Segmentectomy (Y90 RS) using glass microspheres
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Guideline
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  5. Radiology for surgeons: liver anatomy.Frontiers in surgery · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 3 countries.

Amir A BorhaniFrom the Department of Radiology, Northwestern University Feinberg School of Medicine, 676 N Saint Clair St, Arkes Family Pavilion, Suite 800, Chicago, IL 60611 (A.A.B., R.C.); Departments of Radiology (A.A.B., A.F.) and Surgery (A.H.), University of Pittsburgh School of Medicine, Pittsburgh, Pa; Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, Tex (K.M.E.); Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass (A. Kambadakone); Department of Radiology, Weill Cornell Medical Center, New York, NY (A.S.K.); Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (A. Kamath); Department of Radiology, University of Chicago School of Medicine, Chicago, Ill (C.H.); Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, and Department of Radiology, University of São Paulo, São Paulo, Brazil (N.H.); and Department of Radiology, University of Toronto, Toronto, Ontario, Canada (A.Z.K.).ORCID 0000-0001-8963-2984
Khaled M ElsayesFrom the Department of Radiology, Northwestern University Feinberg School of Medicine, 676 N Saint Clair St, Arkes Family Pavilion, Suite 800, Chicago, IL 60611 (A.A.B., R.C.); Departments of Radiology (A.A.B., A.F.) and Surgery (A.H.), University of Pittsburgh School of Medicine, Pittsburgh, Pa; Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, Tex (K.M.E.); Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass (A. Kambadakone); Department of Radiology, Weill Cornell Medical Center, New York, NY (A.S.K.); Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (A. Kamath); Department of Radiology, University of Chicago School of Medicine, Chicago, Ill (C.H.); Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, and Department of Radiology, University of São Paulo, São Paulo, Brazil (N.H.); and Department of Radiology, University of Toronto, Toronto, Ontario, Canada (A.Z.K.).ORCID 0000-0003-0184-0717
Roberta CataniaFrom the Department of Radiology, Northwestern University Feinberg School of Medicine, 676 N Saint Clair St, Arkes Family Pavilion, Suite 800, Chicago, IL 60611 (A.A.B., R.C.); Departments of Radiology (A.A.B., A.F.) and Surgery (A.H.), University of Pittsburgh School of Medicine, Pittsburgh, Pa; Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, Tex (K.M.E.); Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass (A. Kambadakone); Department of Radiology, Weill Cornell Medical Center, New York, NY (A.S.K.); Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (A. Kamath); Department of Radiology, University of Chicago School of Medicine, Chicago, Ill (C.H.); Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, and Department of Radiology, University of São Paulo, São Paulo, Brazil (N.H.); and Department of Radiology, University of Toronto, Toronto, Ontario, Canada (A.Z.K.).
Avinash KambadakoneFrom the Department of Radiology, Northwestern University Feinberg School of Medicine, 676 N Saint Clair St, Arkes Family Pavilion, Suite 800, Chicago, IL 60611 (A.A.B., R.C.); Departments of Radiology (A.A.B., A.F.) and Surgery (A.H.), University of Pittsburgh School of Medicine, Pittsburgh, Pa; Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, Tex (K.M.E.); Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass (A. Kambadakone); Department of Radiology, Weill Cornell Medical Center, New York, NY (A.S.K.); Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (A. Kamath); Department of Radiology, University of Chicago School of Medicine, Chicago, Ill (C.H.); Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, and Department of Radiology, University of São Paulo, São Paulo, Brazil (N.H.); and Department of Radiology, University of Toronto, Toronto, Ontario, Canada (A.Z.K.).ORCID 0000-0001-6714-9190
Alessandro FurlanFrom the Department of Radiology, Northwestern University Feinberg School of Medicine, 676 N Saint Clair St, Arkes Family Pavilion, Suite 800, Chicago, IL 60611 (A.A.B., R.C.); Departments of Radiology (A.A.B., A.F.) and Surgery (A.H.), University of Pittsburgh School of Medicine, Pittsburgh, Pa; Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, Tex (K.M.E.); Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass (A. Kambadakone); Department of Radiology, Weill Cornell Medical Center, New York, NY (A.S.K.); Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (A. Kamath); Department of Radiology, University of Chicago School of Medicine, Chicago, Ill (C.H.); Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, and Department of Radiology, University of São Paulo, São Paulo, Brazil (N.H.); and Department of Radiology, University of Toronto, Toronto, Ontario, Canada (A.Z.K.).ORCID 0000-0002-6099-1323
Andrea S KieransFrom the Department of Radiology, Northwestern University Feinberg School of Medicine, 676 N Saint Clair St, Arkes Family Pavilion, Suite 800, Chicago, IL 60611 (A.A.B., R.C.); Departments of Radiology (A.A.B., A.F.) and Surgery (A.H.), University of Pittsburgh School of Medicine, Pittsburgh, Pa; Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, Tex (K.M.E.); Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass (A. Kambadakone); Department of Radiology, Weill Cornell Medical Center, New York, NY (A.S.K.); Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (A. Kamath); Department of Radiology, University of Chicago School of Medicine, Chicago, Ill (C.H.); Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, and Department of Radiology, University of São Paulo, São Paulo, Brazil (N.H.); and Department of Radiology, University of Toronto, Toronto, Ontario, Canada (A.Z.K.).ORCID 0000-0001-9672-1803
Amita KamathFrom the Department of Radiology, Northwestern University Feinberg School of Medicine, 676 N Saint Clair St, Arkes Family Pavilion, Suite 800, Chicago, IL 60611 (A.A.B., R.C.); Departments of Radiology (A.A.B., A.F.) and Surgery (A.H.), University of Pittsburgh School of Medicine, Pittsburgh, Pa; Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, Tex (K.M.E.); Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass (A. Kambadakone); Department of Radiology, Weill Cornell Medical Center, New York, NY (A.S.K.); Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (A. Kamath); Department of Radiology, University of Chicago School of Medicine, Chicago, Ill (C.H.); Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, and Department of Radiology, University of São Paulo, São Paulo, Brazil (N.H.); and Department of Radiology, University of Toronto, Toronto, Ontario, Canada (A.Z.K.).
Carla HarmathFrom the Department of Radiology, Northwestern University Feinberg School of Medicine, 676 N Saint Clair St, Arkes Family Pavilion, Suite 800, Chicago, IL 60611 (A.A.B., R.C.); Departments of Radiology (A.A.B., A.F.) and Surgery (A.H.), University of Pittsburgh School of Medicine, Pittsburgh, Pa; Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, Tex (K.M.E.); Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass (A. Kambadakone); Department of Radiology, Weill Cornell Medical Center, New York, NY (A.S.K.); Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (A. Kamath); Department of Radiology, University of Chicago School of Medicine, Chicago, Ill (C.H.); Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, and Department of Radiology, University of São Paulo, São Paulo, Brazil (N.H.); and Department of Radiology, University of Toronto, Toronto, Ontario, Canada (A.Z.K.).
Natally HorvatFrom the Department of Radiology, Northwestern University Feinberg School of Medicine, 676 N Saint Clair St, Arkes Family Pavilion, Suite 800, Chicago, IL 60611 (A.A.B., R.C.); Departments of Radiology (A.A.B., A.F.) and Surgery (A.H.), University of Pittsburgh School of Medicine, Pittsburgh, Pa; Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, Tex (K.M.E.); Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass (A. Kambadakone); Department of Radiology, Weill Cornell Medical Center, New York, NY (A.S.K.); Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (A. Kamath); Department of Radiology, University of Chicago School of Medicine, Chicago, Ill (C.H.); Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, and Department of Radiology, University of São Paulo, São Paulo, Brazil (N.H.); and Department of Radiology, University of Toronto, Toronto, Ontario, Canada (A.Z.K.).ORCID 0000-0002-3163-9478
Abhinav HumarFrom the Department of Radiology, Northwestern University Feinberg School of Medicine, 676 N Saint Clair St, Arkes Family Pavilion, Suite 800, Chicago, IL 60611 (A.A.B., R.C.); Departments of Radiology (A.A.B., A.F.) and Surgery (A.H.), University of Pittsburgh School of Medicine, Pittsburgh, Pa; Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, Tex (K.M.E.); Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass (A. Kambadakone); Department of Radiology, Weill Cornell Medical Center, New York, NY (A.S.K.); Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (A. Kamath); Department of Radiology, University of Chicago School of Medicine, Chicago, Ill (C.H.); Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, and Department of Radiology, University of São Paulo, São Paulo, Brazil (N.H.); and Department of Radiology, University of Toronto, Toronto, Ontario, Canada (A.Z.K.).
Ania Z KielarFrom the Department of Radiology, Northwestern University Feinberg School of Medicine, 676 N Saint Clair St, Arkes Family Pavilion, Suite 800, Chicago, IL 60611 (A.A.B., R.C.); Departments of Radiology (A.A.B., A.F.) and Surgery (A.H.), University of Pittsburgh School of Medicine, Pittsburgh, Pa; Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, Tex (K.M.E.); Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass (A. Kambadakone); Department of Radiology, Weill Cornell Medical Center, New York, NY (A.S.K.); Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY (A. Kamath); Department of Radiology, University of Chicago School of Medicine, Chicago, Ill (C.H.); Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, and Department of Radiology, University of São Paulo, São Paulo, Brazil (N.H.); and Department of Radiology, University of Toronto, Toronto, Ontario, Canada (A.Z.K.).ORCID 0000-0001-6887-5266
Northwestern University · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Pittsburgh Liver Research CenterP30DK120531 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Gavin E Arteel · 2019 to 2026
$10.9M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

The need for liver transplants is increasing because the prevalence of liver diseases and the indications for transplants are growing. In response to the shortage of grafts from deceased donors, more transplants are being performed worldwide with grafts from living donors. Radiologic evaluation is an integral component in the assessment of donor candidates to ensure their eligibility and to choose the most appropriate surgical approach. MRI is the preferred modality for evaluation of the liver parenchyma and biliary tree. In most centers, a combination of MRI and CT is used to take advantage of the higher spatial resolution of CT for evaluation of arteries. However, MRI-only assessment is feasible. In addition to assessment of the liver parenchyma for abnormalities such as steatosis, a detailed evaluation of the hepatic vascular and biliary system for pertinent anatomic variants is crucial, because these variants can affect surgical techniques and outcomes in both recipients and donors. In this pictorial article, after a brief review of the most common surgical techniques and postsurgical liver anatomy, the biliary and vascular anatomy are discussed, with specific attention paid to the variants that are pertinent to this surgical procedure. The roles of liver segmentation and volumetric assessment and current imaging techniques and protocols are also discussed.

Indexed as

Liver DiseasesLiver TransplantationHumansLiverLiving DonorsMagnetic Resonance Imaging

Identifiers

PMID34597229
PMCPMC9478886
OpenAlexW3203181680

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.