ArticleAmerican journal of physiology. Heart and circulatory physiology2021
Chronic
Open access · greenAbstract read
In one paragraph
Article in American journal of physiology. Heart and circulatory physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 8% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Guidelines for in vivo mouse models of myocardial infarction.American journal of physiology. Heart and circulatory physiology · 2021Guideline
- Cellular and molecular signals of cardiac wound healing after myocardial infarction.American journal of physiology. Heart and circulatory physiology · 2026Review
- Investigating the Role of TNFSF12 in Thyroid Cancer Progression via Single-Cell RNA Sequencing and Integrated Multiomics Analyses.Mediators of inflammation · 2026Article
- Mesoporous bioactive glass-recombinant collagen III nanocomposite capsule promotes skin wound healing via adaptive immune modulation.Regenerative biomaterials · 2026Article
- Immune Mechanisms in Myocardial Remodeling Following Myocardial Infarction: Focusing on Regulatory Networks of T Cell Responses.Journal of inflammation research · 2026Review
- Review
- The plasma lipopolysaccharide level is associated with contrast-induced acute kidney injury in patients with ST-segment elevation myocardial infarction.BMC cardiovascular disorders · 2025Observational
- Loss of neurofibromin induces inflammatory macrophage phenotypic switch and retinal neovascularization via GLUT1 activation.Cell reports · 2025Article
- Bioinformatics-based Analysis and Verification of Chromatin Regulators and the Mechanism of Immune Infiltration Associated with Myocardial Infarction.Current medicinal chemistry · 2025Article
- Macrophage polarization in acute myocardial infarction: multidimensional regulation and emerging therapeutic opportunities.Frontiers in immunology · 2025Review
- Oral microbiota in cardiovascular health and disease.Frontiers in cellular and infection microbiology · 2025Review
- Article
- Sex as a biological variable for cardiovascular physiology.American journal of physiology. Heart and circulatory physiology · 2024Review
- ERG mediates the inhibition of NK cell cytotoxicity through the HLX/STAT4/Perforin signaling pathway, thereby promoting the progression of myocardial infarction.Journal of physiology and biochemistry · 2024Article
- An eNAMPT-neutralizing mAb reduces post-infarct myocardial fibrosis and left ventricular dysfunction.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2024Article
- Consensus Clustering Analysis Identifies Ferroptosis-Related Patient Clusters and Predictive Signature Construction Based on Ferroptosis-Related Genes in Ischemic Cardiomyopathy.Journal of inflammation research · 2024Article
- A review of the historical use of sex as a biological variable in theAmerican journal of physiology. Heart and circulatory physiology · 2023Review
- Regulation of cardiac fibroblasts by lymphocytes after a myocardial infarction: playing in the major league.American journal of physiology. Heart and circulatory physiology · 2023Review
- We asked and you answered.American journal of physiology. Heart and circulatory physiology · 2023Article
- The cardiac wound healing response to myocardial infarction.WIREs mechanisms of disease · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 2 institutions in 1 country.
Yusra ZaidiDivision of Cardiology, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina.
Alexa CorkerDivision of Cardiology, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina.
Valeriia Y VasilevaDivision of Nephrology, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina.
Kimberly OviedoDivision of Cardiology, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina.
Connor GrahamDepartment of Regenerative Medicine and Cell Biology, Medical University of South Carolina, Charleston, South Carolina.
Kyrie WilsonDepartment of Ophthalmology, Medical University of South Carolina, Charleston, South Carolina.
John MartinoDivision of Cardiology, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina.
Miguel TroncosoDivision of Cardiology, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina.
Philip BroughtonDivision of Cardiology, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina.
Daria V IlatovskayaDivision of Nephrology, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina.
Merry L LindseyDepartment of Cellular and Integrative Physiology, Center for Heart and Vascular Research, University of Nebraska Medical Center, Omaha, Nebraska.ORCID 0000-0002-4090-0391
Kristine Y DeLeon-PennellDivision of Cardiology, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina.ORCID 0000-0002-9647-6112
Medical University of South Carolina · USVA Nebraska Western Iowa Health Care System · US
Funding
Tracking and Evaluation CoreU54GM115458 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI GUDA, CHITTIBABU · 2016 to 2025
$42.8MSouth Carolina Clinical & Translational Research Institute (SCTR)UL1TR001450 · NCATS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BRADY, KATHLEEN T., FLUME, PATRICK A · 2015 to 2024
$41.1MThe Impact of Stress and Craving on Return to Postpartum Cannabis UseU54DA016511 · NIDA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI Nathaniel Lee Baker · 2018 to 2026
$15.9MTraining In Cardiovascular Physiology & PharmacologyT32HL007444 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Ju Chen, Robert Scott Ross · 1985 to 2026
$11.1MCellular, Biochemical and Molecular Sciences Training Program: Developing the skills and expertise needed for a changing biomedical landscapeT32GM132055 · NIGMS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI Amy D Bradshaw, John P O'Bryan · 2019 to 2026
$3.9MUCSD PRIDE Faculty Development Program in Cardiovascular SciencesR25HL145817 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Robert Scott Ross, Joann Trejo · 2019 to 2026
$3.3MMitochondria-Mediated Effects and Therapeutic Potential of Atrial Natriuretic Peptide in Salt-Sensitive Hypertension Diversity SupplementR01HL148114 · NHLBI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI ILATOVSKAYA, DARIA · 2020 to 2024
$2.8MMUSC Post-Baccalaureate Research Education ProgramR25GM113278 · NIGMS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI DELEON-PENNELL, KRISTINE Y, PENROD-MARTIN, RACHEL · 2015 to 2024
$2.7MMMP-12 as an Endogenous Post-MI Resolution Promoting FactorR01HL137319 · NHLBI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI LINDSEY, MERRY L. · 2019 to 2022
$1.5MStructural Modeling of Multifarious Protein ComplexesR01GM123055 · NIGMS · PURDUE UNIVERSITY · PI KIHARA, DAISUKE · 2017 to 2020
$1.2MReplacement of Small Animal Echocardiographic InstrumentationS10OD010417 · OD · VETERANS MEDICAL RESEARCH FDN/SAN DIEGO · PI ROSS, ROBERT SCOTT · 2012 to 2012
$371kNeutrophil Polarization Following Myocardial InfarctionI01BX000505 · VA · VETERANS HEALTH ADMINISTRATION · PI LINDSEY, MERRY L. · 2009 to 2024
–BLRD VA I01 BX000505BLRD VA IK2 BX003922NCATS NIH HHS UL1 TR001450NHLBI NIH HHS R01 HL137319NHLBI NIH HHS R01 HL148114NHLBI NIH HHS R25 HL145817NHLBI NIH HHS T32 HL007444NIDA NIH HHS U54 DA016511NIGMS NIH HHS R01 GM123055NIGMS NIH HHS R25 GM113278NIGMS NIH HHS T32 GM132055NIGMS NIH HHS U54 GM115458NIH HHS S10 OD010417
Abstract
Oral and gum health have long been associated with incidence and outcomes of cardiovascular disease. Periodontal disease increases myocardial infarction (MI) mortality by sevenfold through mechanisms that are not fully understood. The goal of this study was to evaluate whether lipopolysaccharide (LPS) from a periodontal pathogen accelerates inflammation after MI through memory T-cell activation. We compared four groups [no MI, chronic LPS,
Indexed as
Immunologic MemoryLipopolysaccharidesLymphocyte ActivationPorphyromonas gingivalisWound HealingAnimalsCD8-Positive T-LymphocytesCells, CulturedDisease Models, AnimalFemaleInflammation MediatorsMacrophagesMaleMiceMyocardial InfarctionMyocardiumInflammation MediatorsLipopolysaccharidescardiovascular diseasememory immune responsemyocardial infarctionperiodontal diseaseT cells
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What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.